Adsorptive Stripping Voltammetric Determination of Mangiferin Using an Activated Chitosan Modified Carbon Paste Electrode

Francis Merlin Melataguia Tchieno, Evangeline Njanja, Léon Azefack Tapondjou, Ignas Kenfack Tonle

Electrochemistry and Chemistry of Materials, Department of Chemistry, University of Dschang, Dschang, Cameroon.
Laboratory of Applied and Environmental Chemistry, Department of Chemistry, University of Dschang, Dschang, Cameroon.

DOI: 10.4236/ajac.2014.57051                

Abstract

A medium molecular weight powdered chitosan modified carbon paste electrode was used to investigate the electrochemical behaviour by cyclic voltammetry of the pharmacologically-active ingredient mangiferin (MG). An irreversible system was observed, with a peak at ﹢0.55 V (vs Ag/AgCl). The peak current increases about fourfold, at the modified electrode in comparison with that recorded at the chitosan free carbon paste electrode. This allowed the use of adsorptive stripping voltammetry to develop a simple and sensitive electroanalytical method for the determination of MG. The influence of key parameters was investigated, including the electrolysis potential, the preconcentration time, the pH of supporting electrolyte and MG concentration. Upon optimisation of these parameters, the electrode response was found to be directly proportional to the concentration of MG in the range from 2.06 × 10^﹣6 M to 6.74 × 10^﹣5 M, leading to a detection limit of 1.84 μM for 240 s preconcentration at ﹣0.1 V. A mechanism was also proposed for the electrochemical oxidation of MG.

Keywords

Mangiferin (Mangifera indica L.), Xanthones, Carbon Paste Electrode, Chitosan, Stripping Voltammetry

Conflicts of Interest

The authors declare no conflicts of interest.

References

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