Ability of Comprehensive Geriatric Assessment to Detect Frailty

DOI: 10.4236/aar.2014.32011   PDF   HTML     4,271 Downloads   6,481 Views   Citations


Background and Aim of the Work: Frailty is a state of reduced physiological reserve associated with increased susceptibility to disability. It is associated with a high morbidity and mortality. This work assessed the ability of comprehensive geriatric assessment to detect frailty in elderly patients. Subjects and Methods: A total number of 104 elderly patients (above 60 years old) were included in this study and they were subjected to a comprehensive geriatric assessment (CGA) including: (history and full clinical examination, Mini mental status examination (MMSE), Geriatric depression scale (GDS), Activities of daily living (ADL), Instrumental activities of daily living (IADL). The patients were divided into frail and non-frail groups using Fried’s criteria as applied by Avila-Funes et al., 2008, each group included 52 patients. Results: There were no significant differences between the two groups regarding age gender or smoking habits. But there was higher percentage of ADL, IADL dependence in addition to higher incidence of depression and cognitive impairment among frail cases. Conclusion: Comprehensive geriatric assessment can be used to detect frailty and its associated impairment and comorbidities.

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Amer, M. , Farid, T. , El-Rahman, E. , EL-Maleh, D. , Omar, O. and Mabrouk, R. (2014) Ability of Comprehensive Geriatric Assessment to Detect Frailty. Advances in Aging Research, 3, 63-69. doi: 10.4236/aar.2014.32011.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Fried, L.P. and Walston, J. (2003) Frailty and Failure to Thrive. In: Hazzard, W., Blass, J.P., Halter, J.B., et al., Eds., Principles of Geriatric Medicine and Gerontology, 5th Edition, McGraw-Hill, New York, 1487-1502.
[2] Lipschitz, S. (2007) Comprehensive Geriatric Assessment. African Journals Online, CME, 25, 418-420.
[3] Rockwood, K. and Hubbard, R. (2004) Frailty and the Geriatrician. Age and Ageing, 33, 429-430.
[4] Fried, L.P., Tangen, C.M., Walston, J., et al. (2001) Cardiovascular Health Study Collaborative Research Group. Frailty in Older Adults: Evidence for a Phenotype. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 56, M146-M156.
[5] Avila-Funes, J.A., Helmer, C., Amieva, H., et al. (2008) Frailty among Community-Dwelling Elderly People in France: The Three-City Study. Journal of Gerontology: Medical Sciences by the Gerontological Society of America, 63A, 1089-1096.
[6] Folstein, M., Folstein, S. and McHug, P. (1975) Minimental State. A Practical Method for Gradient the Cognitive State of Patients for Clinicians. Journal of Psychiatric Research, 12, 189-198.
[7] El-Okl, M. (2002) Prevalence of Alzheimer Dementia and Other Causes of Dementia in Egyptian Elderly. Dissertation, Ain Shams University, Cairo.
[8] Sheikh, J. and Yesavage, J. (1986) Geriatric Depression Scale (GDS) Recent Evidence and Development of a Shorter Version. Clinical Gerontology, 5, 165-173.
[9] Shehta, A.S., El-Banouby, M.H., Mortagy, A.K., et al. (1998) Prevalence of Depression among Egyptian Geriatric Community. Geriatric Department Library, Ain Shams University, Cairo, 3-5.
[10] Katz, S., Ford, A., Moswowitz, R., Jackson, B. and Jaffe, M. (1963) Studies of Illness in the Aged. The Index of ADL: Standardized Measure of Biological and Psychological Function. The Journal of the American Medical Association, 185, 914-919. http://dx.doi.org/10.1001/jama.1963.03060120024016
[11] El-Sherpiny, M., Mortagy, A. and Fahy, H. (2000) Prevalence of Hypercholesterolemia among Elderly People Living in Nursing Houses in Cairo. Geriatric Department Library, Ain Shams University, Cairo, 6.
[12] Lawton, M. and Brody, E. (1969) Assessment of Older People: Self-Maintaining and Instrumental Activities of Daily Living. The Gerontologist, 9, 179-186.
[13] Fillenbaum, G. (1986) The Wellbeing of the Elderly: Approaches to Multi-Dimensional Assessment. World Health Organization, WHO Offset Publication No. 84, Arabic Translation Distributed by the Eastern Mediterranean Regional Office.
[14] Fried, L., Kronmal, R., Newman, A., et al. (1998) Risk Factors for 5 Year Mortality in Older Adults: The Cardiovascular Health Study. The Journal of the American Medical Association, 279, 585-592.
[15] Inaki, M., Iturbe, A., Gome, J., et al. (2010) The Frail Elderly, Detection and Treatment. Aten Primaria, 42, 388-339.
[16] Ottenbacher, K.J., Ostir, G.V., Peek, M.K., et al. (2005) Frailty in Older Mexican Americans. Journal of the American Geriatrics Society, 53, 1524-1531. http://dx.doi.org/10.1111/j.1532-5415.2005.53511.x
[17] Ensrud, K.E., Ewing, S.K., Taylor, B.C., et al. (2008) Comparison of 2 Frailty Indexes for Prediction of Falls, Disability, Fractures, and Death in Older Women. Archives of Internal Medicine, 168, 382-389.
[18] Fried, L.P., Xue, Q.L., Cappola, A.R., et al. (2009) Nonlinear Multisystem Physiological Dysregulation Associated with Frailty in Older Women: Implications for Etiology and Treatment. The Journals of Gerontology: Series A, Biological Sciences and Medical Sciences, 64, 1049-1057. http://dx.doi.org/10.1093/gerona/glp076
[19] Ternent, S.R., Karmarkar, A., Graham, J., Reistetter, T. and Ottenbacher, K. (2012) Frailty as a Predictor of Falls in Older Mexican Americans. Journal of Aging and Health, 24, 641-653. http://dx.doi.org/10.1177/0898264311428490
[20] Wiess, C.O. (2011) Frailty and Chronic Diseases in Older Adults. Clinics in Geriatric Medicine, 27, 39-52.
[21] Bandeen-Roche, K., Xue, Q.L., Ferrucci, L., et al. (2006) Phenotype of Frailty: Characterization in the Women’s Health and Aging Studies. The Journals of Gerontology: Series A, Biological Sciences and Medical Sciences, 61, 262-266.
[22] Nourhashémi, F., Andrieu, S., Gillette-Guyonnet, S., et al. (2001) Instrumental Activities of Daily Living as a Potential Marker of Frailty: A Study of 7364 Community-Dwelling Elderly Women (the EPIDOS Study). The Journals of Gerontology: Series A, Biological Sciences and Medical Sciences, 56, M448-M453.
[23] Chen, C.Y., Wub, S.C., Chenb, L.J., et al. (2010) The Prevalence of Subjective Frailty and Factors Associated with Frailty in Taiwan. Archives of Gerontology and Geriatrics, 50, 43-47.
[24] Aron, S.B., Patricia, A.B., Robert, S.W., et al. (2007) Frailty is Associated with Incident Alzheimer’s Disease and Cognitive Declinein the Elderly. Psychosomatic Medicine, 69, 483-489.
[25] Garrido, M.S., and Ponce, C.G. (2012) Ability of the Comprehensive Geriatric Assessment to Predict Frailty in Older People Diagnosed with Cancer in a General Hospital. European Oncology & Haematology, 8, 85-88.
[26] Bilotta, C., Bowling, A., Casè, A., et al. (2010) Desiemensions and Correlates of Quality of Life According to Frailty Status: A cross-Sectional Study on Community-Dwelling Older Adults Referred to an Outpatient Geriatric Service in Italy. Health and Quality of Life Outcomes, 8, 56-63. http://dx.doi.org/10.1186/1477-7525-8-56
[27] Ottenbacher, K.J., Ostir, G.V., Peek, M.K., et al. (2005) Frailty in Mexican American Older Adults. Journal of the American Geriatrics Society, 53, 1524-1531. http://dx.doi.org/10.1111/j.1532-5415.2005.53511.x
[28] Mitnitski, A., Song, X., Skoog, I., et al. (2005) Relative Fitness and Frailty of Elderly Men and Women in Developed Countries and Their Relationship with Mortality. Journal of the American Geriatrics Society, 53, 2184-2189.
[29] Jones, D.M., Song, X. and Rockwood, K. (2004) Operationalizing a Frailty Index from a Standardized Comprehensive Geriatric Assessment. Journal of the American Geriatrics Society, 52, 1929-1933.

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