Extraction Process Validation of Isatis Radix

Junshan Li; Bo Zhang

doi:10.4236/pp.2014.54043

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Pharmacology & Pharmacy > Vol.5 No.4, April 2014

Extraction Process Validation of Isatis Radix ()

Junshan Li, Bo Zhang

Shineway Pharmaceutical Group Ltd., Shijiazhuang, China.

DOI: 10.4236/pp.2014.54043 PDF HTML XML 4,340 Downloads 5,347 Views Citations

Abstract

This study is aimed to validate the extraction process of Isatis Radix. Using near infrared spectroscopy and high performance liquid chromatography to determine the uridine, adenosine, guanosine contents in Isatis Radix Solution, as well as NIR to monitor the extraction process. The results indicate that the existing extraction is optimized to extract thoroughly.

Keywords

Isatis Radix; Extraction Process; NIR Spectroscopy; HPLC; Validation

Share and Cite:

Li, J. and Zhang, B. (2014) Extraction Process Validation of Isatis Radix. Pharmacology & Pharmacy, 5, 356-363. doi: 10.4236/pp.2014.54043.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	China Pharmacopoeia Committee (2010) Chinese Pharmacopoeia, Volume I, PRC. Chinese Medical Science and Technology Press, Beijing, 191.
[2]	Zhang, H.Y. (2010) Clinical Application of Decoction of TCM Formula Granule. Journal of North China Coal Medical University, 12, 496-498.