Extraction Process Validation of Isatis Radix

Junshan Li; Bo Zhang

doi:10.4236/pp.2014.54043

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PP> Vol.5 No.4, April 2014

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Extraction Process Validation of Isatis Radix

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DOI: 10.4236/pp.2014.54043 4,168 Downloads 5,134 Views Citations

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Junshan Li, Bo Zhang

Affiliation(s)

Shineway Pharmaceutical Group Ltd., Shijiazhuang, China.

ABSTRACT

This study is aimed to validate the extraction process of Isatis Radix. Using near infrared spectroscopy and high performance liquid chromatography to determine the uridine, adenosine, guanosine contents in Isatis Radix Solution, as well as NIR to monitor the extraction process. The results indicate that the existing extraction is optimized to extract thoroughly.

KEYWORDS

Isatis Radix; Extraction Process; NIR Spectroscopy; HPLC; Validation

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Li, J. and Zhang, B. (2014) Extraction Process Validation of Isatis Radix. Pharmacology & Pharmacy, 5, 356-363. doi: 10.4236/pp.2014.54043.

References

[1]	China Pharmacopoeia Committee (2010) Chinese Pharmacopoeia, Volume I, PRC. Chinese Medical Science and Technology Press, Beijing, 191.

[2]	Zhang, H.Y. (2010) Clinical Application of Decoction of TCM Formula Granule. Journal of North China Coal Medical University, 12, 496-498.