Effect of Carbohydrate Intolerance and Gestational Diabetes on Obstetric and Perinatal Outcomes

Leticia Lara-Ávila, José Manuel Brambila-Durán, Diego Armando Camacho-Ramírez, Felipe de Jesús Peraza-Garay, Adrián Herrera-Salazar, Fred Morgan-Ortiz

Health Sciences Research and Teaching Center, Autonomous University of Sinaloa, Civil Hospital of Culiacan, Culiacan, Mexico.

DOI: 10.4236/ojog.2014.46040                

Abstract

Objectives: To compare the frequency of obstetric and perinatal complications among patients with carbohydrate intolerance (CHI) and gestational diabetes (GD). Materials and Methods: In a prospective study at the Civil Hospital of Culiacán, we studied 182 pregnant patients between 16 and 30 weeks of gestation (WG) who received a glucose tolerance test following the oral administration of 100 g of glucose. The patients were classified as normal (n = 53), CHI (n = 61) and GD (n = 68) between January 15 to November 30, 2012. The analyzed variables included the frequency of polyhydramnios, preeclampsia-eclampsia, obstetric hemorrhage, fetal macrosomia, and admission to a neonatal intensive care unit (NICU). Results: No significant differences were found between women with CHI and women with GD with respect to obstetric hemorrhage (P = 0.774), preeclampsia-eclampsia (P = 0.590), and macrosomia (P = 0.119). However, polyhydramnios was more frequent in CHI group (OR = 3) compared to GD, whereas admission to the NICU was lower in the CHI group compared to GD group (OR = 0.38). Conclusion: Preeclampsia-eclampsia, obstetric hemorrhage, and macrosomia were similar among patients with CHI and GD. In contrast, polyhydramnios was more frequent in patients with CHI compared to patients with GD, but admission to the NICU was more frequent in patients with GD.

Keywords

Glucose Tolerance Test; Carbohydrate Intolerance; Gestational Diabetes; Perinatal Outcome

Conflicts of Interest

The authors declare no conflicts of interest.

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