Metastatic Rectal Adenocarcinoma of the Hip and Knee Joints: A Case Series


Two cases are presented of patients with a history of metastatic rectal adenocarcinoma presenting with a painful joint effusion. Both cases are potential examples of metastasis to periarticular bone with local infiltration to the synovium, which is one proposed mechanism of intrasynovial metastasis. While skeletal metastases are a relatively common occurrence in metastatic adenocarcinoma, intraarticular metastasis is extremely rare. These cases highlight the need to consider metastasis in the differential of joint swelling in the setting of a history of adenocarcinoma.

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Rothenberg, A. , Henrikson, K. , Schiffman, S. and Goodman, M. (2014) Metastatic Rectal Adenocarcinoma of the Hip and Knee Joints: A Case Series. Journal of Cancer Therapy, 5, 323-330. doi: 10.4236/jct.2014.54039.

Conflicts of Interest

The authors declare no conflicts of interest.


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