Treatment success rate of tuberculosis patients in Dabat, northwest Ethiopia

Abstract

Evaluating the outcomes of DOTS program is essential for recognizing and amending system failures before the incidence and proportion of resistant isolates rise. In this study, we seek to evaluate the impact of DOTS strategy on tuberculosis treatment success rate in Dabat, northwest Ethiopia. Medical records of 1305 pulmonary and extrapulmonary tuberculosis patients registered from 2007 to 2012 at two health centers in Dabat district, northwest Ethiopia, were reviewed. Treatment outcomes and forms of tuberculosis were assessed according to WHO guidelines. Descriptive analyses were performed using frequencies and percentages. Treatment success rate was observed in 1146 (87.8%) patients. Out of these, 534 (89.1%) of the males and 612 (86.7%) of the females were successfully treated. It was also true in 338 (87.8%) of the smear-positive pulmonary tuberculosis patients, 473 (85.7%) of the smear-negative pulmonary tuberculosis patients, and 335 (91.0%) of the extrapulmonary tuberculosis patients. In conclusion, treatment success rate in the current study was slightly higher than the WHO international updated target for the period 2011 to 2015. However, this doesn’t mean that there will be no need for further enhancement of supervision and monitoring techniques, strengthening counseling and health education programs, and improving the quality of laboratory diagnostic services.

Share and Cite:

Tadesse, S. and Tadesse, T. (2014) Treatment success rate of tuberculosis patients in Dabat, northwest Ethiopia. Health, 6, 306-310. doi: 10.4236/health.2014.65044.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] World Health Organization (2011) Global tuberculosis control. World Health Organization, Geneva.
[2] World Health Organization (2010) Global tuberculosis control. World Health Organization, Geneva.
[3] World Health Organization (2012) Global tuberculosis control. World Health Organization, Geneva.
[4] Tadesse, T., Demissie, M., Berhane, Y., Kebede, Y. and Abebe, M. (2011) Two-thirds of smear-positive tuberculosis cases in the community were undiagnosed in Northwest Ethiopia: Population-based cross-sectional study. PLoS One, 6, 28258.
http://dx.doi.org/10.1371/journal.pone.0028258
[5] Federal Ministry of Health (2011) Health and health related indicators, Ethiopia. Federal Ministry of Health, 37.
[6] Federal Ministry of Health (2011) Overview of National TB Control Implementation status. Sixth National TB Research Workshop, Gondar University, Gondar.
[7] Berhe, G., Enquselassie, F. and Aseffa, A. (2012) Treatment outcome of smear-positive pulmonary tuberculosis patients in Tigray Region, Northern Ethiopia. BMC Public Health, 12, 537.
http://dx.doi.org/10.1186/1471-2458-12-537
[8] Munoz, S.M., Cuevas, L.E., Tumato, M., Merid, Y. and Yassin, M.A. (2010) Factors associated with poor tuberculosis treatment outcome in the Southern Region of Ethiopia. The International Journal of Tuberculosis and Lung Disease, 14, 973-979.
[9] Tessema, B., Muche, A., Bekele, A., Reissig, D., Emmrich, F. and Sack U. (2009) Treatment outcome of tuberculosis patients at Gondar University Teaching Hospital, Northwest Ethiopia: A five-year retrospective study. BMC Public Health, 9, 371.
http://dx.doi.org/10.1186/1471-2458-9-371
[10] Veen, J., Raviglione, M., Rieder, H.L., Migliori, G.B., Graf, P., Grzemska, M. and Zalesky, R. (1998) Standardized tuberculosis treatment outcome monitoring in Europe. Recommendations of a Working Group of the WHO and the European Region of the International Union against Tuberculosis and Lung Disease (IUATLD) for uniform reporting by cohort analysis of treatment outcome in tuberculosis patients. European Respiratory Journal, 12, 505-510.
http://dx.doi.org/10.1183/09031936.98.12020505
[11] Tuula, V., Pekka, H., Jukka, O., Kari, L., Maarit, K. and Petri, R. (2007) Risk factors for poor tuberculosis treatment outcome in Finland: a cohort study. BMC Public Health, 7, 291-299.
http://dx.doi.org/10.1186/1471-2458-7-291
[12] Central Statistical Authority (2007) Population and Housing Census of Ethiopia: Results for Amhara Regional State. Addis Ababa.
[13] Ethiopian Federal Ministry of Health (2008) Tuberculosis, Leprosy and TB/HIV Prevention and Control Program Manual. Addis Ababa.
[14] Datiko, D.G. and Lindtjorn, B. (2009) Health Extension Workers improve tuberculosis case detection and treatment success in Southern Ethiopia: A community randomized trial. PLoS One, 4, e5443.
http://dx.doi.org/10.1371/journal.pone.0005443
[15] Van, D.B.J., Lyimo, R., Irongo, C.F., Boeree, M.J., Schaalma, H., Aarnoutse, R.E. and Kibiki, G.S. (2009) Community vs. facility-based directly observed treatment for tuberculosis in Tanzania’s Kilimanjaro Region. The International Journal of Tuberculosis and Lung Disease, 13, 1524-1529.
[16] Getahun, H., Gunneberg, C., Granich, R. and Nunn, P. (2010) HIV infection associated tuberculosis: The epidemiology and the response. Clinical Infectious Diseases, 50, 201-207.
http://dx.doi.org/10.1086/651492
[17] Kwan, C.K. and Ernst, J.D. (2011) HIV and tuberculosis: A deadly human syndemic. Clinical Microbiology Reviews, 24, 351-376.
http://dx.doi.org/10.1128/CMR.00042-10
[18] Deribew, A., Hailemichael, Y., Tesfaye, M., Desalegn, D., Wogi, A. and Daba, S. (2010) The synergy between TB and HIV co-infection on perceived stigma in Ethiopia. BMC Research Notes, 3, 249.
http://dx.doi.org/10.1186/1756-0500-3-249

Copyright © 2023 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.