Benign Fibrous Histiocytoma of the Neurocranium


Presented is a case of benign fibrous histiocytoma (BFH) involving the calvarium of a 25 years old lady who noticed a depression in her occiput associated with localised pain. Imaging revealed a tumour eroding through the inner and outer skull tables, closely associated with major underlying dural sinuses. She underwent complete macroscopic resection of the tumour and reconstruction of a titanium mesh cranioplasty. Histology favoured a benign process with a diagnosis of BFH of the calvarium given. At 1 year follow-up, the patient is asymptomatic and has not developed recurrence of the tumour.

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C. A. Tsimiklis and T. Morris, "Benign Fibrous Histiocytoma of the Neurocranium," Neuroscience and Medicine, Vol. 4 No. 4, 2013, pp. 267-270. doi: 10.4236/nm.2013.44038.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] M. Ideguchi, K. Kajiwara, K. Yoshikawa, S. Kato, M. Fujii, H. Fujisawa and M. Suzuki, “Benign Fibrous Histiocytoma of the Skull with Increased Intracranial Pressure Caused by Cerebral Venous Sinus Occlusion,” Journal of Neurosurgery, Vol. 111, No. 3, 2009, pp. 504-518.
[2] C. D. M. Fletcher, J. A. Bridge, P. Hogendoorn and F. Mertens, “WHO Classification of Tumours of Soft Tissue and Bone,” 4th Edition, Vol. 5, WHO Press, Geneve, 2013.
[3] R. S. Tubbs, D. R. Kelly, J. L. Pugh, M. Loukas and W. J. Oakes, “Benign Fibrous Histiocytoma of the Skull Base,” Journal of Neurosurgery, Vol. 106, 2007, pp. 65-67.
[4] M. Joo, G. J. Lee, Y.-C. Koh, O.-K. Kwon and Y.-K. Park, “Primary Intraosseous Malignant Fibrous Histiocytoma of the Skull: A Case Report,” Journal of Korean Medical Science, Vol. 18, 2003, pp. 609-613.
[5] S. Bieclamowicz, M. S. Dauer, B. Chang and M. C. Zimmerman, “Non-Cutaneous Benign Fibrous Histiocytoma of the Head and Neck,” Otolaryngology Head and Neck Surgery, Vol. 113, No. 1 1995, pp. 140-146.

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