A Clinco-Bacteriological Study of Leprosy in Paediatric Age Group


Clinico-bacteriological study was done in 51 leprosy patients below 14 years of age. Majority of the patients were males in the age group of 11-14 years. Nearly 84% had not received any prior treatment because of lack of awareness and financial constraints. Only 11.76% had a positive contact history. Skin lesions were present in all cases and 84.3% had lesions mainly on the exposed areas of the body and their number was found to increase significantly with advancing age (p < 0.005). These lesions were hypo-pigmented patches in 88% cases. 88% of cases had hypo-anesthesia and nerve thickening was observed in 24% cases. The most common type of skin lesion was borderline tuberculoid (BT) in 53% cases. Positivity of the skin smears increased significantly as the number of the skin lesions per patient increased (p < 0.001). Multibacillary cases were seen in 15.6% of cases and found only in the age group of 10-14 years of age. No statistically significant association between BCG vaccination and prevention of leprosy was seen.

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L. Das, B. Meher, N. Das, D. Pradhan, S. Pradeep and J. Mohanty, "A Clinco-Bacteriological Study of Leprosy in Paediatric Age Group," Advances in Infectious Diseases, Vol. 3 No. 4, 2013, pp. 269-273. doi: 10.4236/aid.2013.34041.

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The authors declare no conflicts of interest.


[1] P. K. Leprosy, “Text Book of Preventive and Social Medicine,” 19th Edition, M/S Banarasi Das bhanot, Jabalpur, pp. 264-278.
[2] World Health Organization, “Global Burden of Leprosy at the End of 2010,” The Weekly Epidemiological Record, Vol. 86, 2011, pp. 389-400.
[3] WHO, “Weekly Epidemiological Record,” No. 28, 2000.
[4] M. B. Disability and Child Proportion, “Epidemiological Significance and Interpretation. National Leprosy Eradication Program Guidelines.” http://nlep.nic.in/guide.html
[5] F. J. Moet, R. P. Schuring, D. Pahan, L. Oskam and J. H. Richardus, “The Prevalence of Previously Undiagnosed Leprosy in the General Population of Northwest Bangladesh,” PLOS Neglected Tropical Diseases, Vol. 2, 2008, p. e198. http://dx.doi.org/10.1371/journal.pntd.0000198
[6] S. Mahajan, K. Sardana, P. Bhushan, R. V. Koranne and V. Mendiratta, “A Study of Leprosy in Children, from a Tertiary Pediatric Hospital in India,” Leprosy Review, Vol. 77, 2006, pp. 160-162.
[7] W. H. Jopling, “Hand Book of Leprosy,” 3rd Edition, William-Heinemann, London, 1984.
[8] Dharmendra, “Leprosy,” Sammat and Company, Bombay, 1985.
[9] R. Dayal, A. K. Paliwal, R. Prasad, et al., “A ClinicoBacteriological Profile of Leprosy in Children,” Indian Paediatric, Vol. 26, 1989, pp. 122-128.
[10] R. Dayal, P. K. Agarwal, K. Katra, et al., “Diagnostic Value of Gene Probes and Its Co-Relation with Clinical Profile of Leprosy in Children,” Indian Pediatrics, Vol. 31, 1994, pp. 1521-1527.
[11] A. Selvasekhar, J. Geetha, K. Nisha, N. Manimozhi, K. Jesudas and P. S. Rao, “Childhood Leprosy in an Endemic Area,” Leprosy Review, Vol. 70, No. 1, 1999, pp. 21-27.
[12] R. Dayal, “Leprosy in Childhood,” Recent Advances in Pediatrics, Vol. 1, 1991, p. 258.
[13] V. N. Sehgal and A. N. Chaudhary, “Leprosy in Children, A Prospective Study,” 1993.
[14] C. Grover, S. Nanda, V. K. Garg and B. S. Reddy, “An Epidemiologic Study of Childhood Leprosy from Delhi,” Pediatric Dermatology, Vol. 22, 2005, pp. 489-490.
[15] I. Kaur, S. Kaur, V. K. Sharma and B. Kumar, “Childhood Leprosy in Northern India,” Pediatric Dermatology, Vol. 8, 1991, pp. 21-24.
[16] N. Vara, “Profile of New Cases of Childhood Leprosy in a Hospital Setting,” Indian Journal of Leprosy, Vol. 78, No. 3, 2006, pp. 17-22.
[17] R. Roy and G. Kalla, “Pattern of Leprosy in Children in Jodhpur,” Indian Journal of Leprosy, Vol. 69, No. 2, 1997, pp. 199-200.
[18] Van Braket Wh, et al., “Leprosy Review,” Vol. 63, 1992, pp. 231-235.
[19] B. S. Bhavasar and N. R. Meheta, “An Epidemiological of Leprosy through School Survey in Surat Dist. (SouthGujurat),” Leprosy in India, Vol. 52, 1980, pp. 548-546.
[20] A. Singal, S. Sonthalia and D. Pandhi, “Childhood Leprosy in a Tertiary-Care Hospital in Delhi, India: A Reappraisal in the Post-Elimination Era,” Leprosy Review, Vol. 82, 2011, pp. 259-269.
[21] V. P. Shetty, S. D. Ghate, A. V. Wakade, D. V. Thakur, U. H. Thakar and E. D’souza, “Clinical, Bacteriological, and Histopathological Characteristics of Newly Detected Children with Leprosy: A Population Based Study in a Defined Rural and Urban Area of Maharashtra, Western India,” Indian Journal of Dermatology, Venerology, Leprology, Vol. 79, No. 4, pp. 512-519.
[22] WHO, “Technical Report Series,” 1988, p. 768.

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