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Breast Density: Does It Vary among the Main Ethnic Groups in Malaysia?

Abstract Full-Text HTML Download Download as PDF (Size:127KB) PP. 105-109
DOI: 10.4236/ojmi.2013.34017    3,366 Downloads   5,432 Views   Citations
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Kanaga Kumari Chelliah, Noor Shatirah Mohd Fandi Voon, Hanizan Ahamad

Affiliation(s)

Diagnostic Imaging and Radiotherapy Programme, Health Sciences Faculty, National University of Malaysia, Kuala Lumpur, Malaysia.
Radiology Department, University Malaya Medical Centre, Kuala Lumpur, Malaysia.

ABSTRACT

Breast cancer is one of the common cancers among Malaysians and there are associated risk factors which include breast density. Therefore, this study was done to determine the association of breast cancer risks among ethnic groups in relation to breast density. Mammography was done on 300 women with equal numbers of Malays, Chinese and Indians with a mean age of 53.35 ± 7.4 years. Mammograms were evaluated using BI-RADS (Breast Imaging Reporting and Data System) protocol by two independent radiologists for breast density categorization. Chi-square analysis showed an association between breast density and age factor (p < 0.05) whereas body mass index (BMI) was inversely associated with breast density (p > 0.05). There was significant difference in number of children and menopausal status (p < 0.05). Results showed that 65% of Chinese subjects had denser breast density composition as to 50% in Malays and 35% in Indians. There was significant difference between breast density of three ethnic groups (p < 0.05) with Chinese having 2.4 times denser breast (OR = 2.45, 95% CI: 1.466 - 3.948) followed by Malays (OR = 1.020, 95% CI: 0.681 - 1.689) and lowest in Indians (OR = 0.406, 95% CI: 0.247 - 0.668). Based on breast density, the Chinese are at a higher risk of developing breast cancer followed by Malays and lastly Indians.

KEYWORDS

Breast Cancer; Ethnic Groups; Breast Density; Mammogram; BIRADS

Cite this paper

K. Kumari Chelliah, N. Shatirah Mohd Fandi Voon and H. Ahamad, "Breast Density: Does It Vary among the Main Ethnic Groups in Malaysia?," Open Journal of Medical Imaging, Vol. 3 No. 4, 2013, pp. 105-109. doi: 10.4236/ojmi.2013.34017.

Conflicts of Interest

The authors declare no conflicts of interest.

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