Thermodynamical Approach for Choosing the Carrier System for Tetraantraquinoporphyrazines

Natalia Lebedeva, Elena Malkova, Yury Gubarev, Anatoly V’yugin, Albert Borisov

G.A. Krestov Institute of Solution Chemistry of the Russian Academy of Sciences, Ivanovo, Russia.
Ivanovo State University of Chemistry and Technology, Ivanovo, Russia.

DOI: 10.4236/ijoc.2013.34031                

Abstract

On the example of tetraantraquinoporphyrazines—potential photosensitizers for photodynamic therapy, thermodynamic approach to the choice of exogenous transport system was demonstrated. By means of isothermal titration calorimetry and electron absorption spectroscopy, the state of TAP in aqueous solutions was studied. The possibility of aggregation equilibrium displacement due to the pyridine adding was evaluated.

 

Keywords

Tetraantraquinoporphyrazines; Macroheterocycles; Dimerization; Complexation; Self-Aggregation; Transport Systems

Conflicts of Interest

The authors declare no conflicts of interest.

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