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New Method for the Synthesis of 1-Methylimidazolium Trifluoroacetate and Its Application in Biginelli Reaction

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DOI: 10.4236/gsc.2013.34A003    3,326 Downloads   4,986 Views   Citations
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Khan M. Hua, Thach N. Le

Affiliation(s)

Department of Organic Chemistry, Faculty of Chemistry, University of Science, Vietnam National University-Ho Chi Minh City, Ho Chi Minh City, Vietnam.

ABSTRACT

A new method for the synthesis of 1-methylimidazolium trifluoroacetate ([Hmi]Tfa), a protic ionic liquid (PIL), under ultrasonic irradiation has been developed. In addition, the product [Hmi]Tfa was successfully employed as solvent and catalyst in Biginelli reaction to prepare 3,4-dihydropyrimidinones (DHPMs) in high yield under mild reaction conditions.

KEYWORDS

Biginelli Reaction; Microwave Irradition; 1-Methylimidazolium Trifuoroacetate; Protic Ionic Liquid; Oxo-Monastrol; Ultrasonic Irradiation

Cite this paper

K. M. Hua and T. N. Le, "New Method for the Synthesis of 1-Methylimidazolium Trifluoroacetate and Its Application in Biginelli Reaction," Green and Sustainable Chemistry, Vol. 3 No. 4A, 2013, pp. 14-17. doi: 10.4236/gsc.2013.34A003.

Conflicts of Interest

The authors declare no conflicts of interest.

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