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Unusual Metastases from a Pleomorphic Adenoma of the Parotid Gland: A Case and Literature’s Review

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DOI: 10.4236/ijohns.2013.26048    2,943 Downloads   4,144 Views   Citations


Background: Pleomorphic adenoma constitutes the most common benign parotid gland tumor. Local recurrence after surgery has been described in 1%-5% of cases, and malignant evolution in 2%-9% of cases. Metastasizing pleomorphic adenomas has rarely been reported. No histologic or molecular parameters exist at the present time that could predict the development of metastasis in these neoplasms. Methods and Results: A 54-year-old woman had a superficial left parotidectomy with facial nerve preservation for pleomorphic adenoma. She developed two recurrences in 2000 and 2001, but 25 years later the first operation she presented a metastasis in her right gluteal region with evidence of local recurrence. Conclusion: Metastatizing pleomorphic adenoma is a rare pathologic situation but, in case of swelling or lump appearance in patients with pleomorphic adenoma history, it should be taken in mind.

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The authors declare no conflicts of interest.

Cite this paper

G. Mannelli, L. Rucci and O. Gallo, "Unusual Metastases from a Pleomorphic Adenoma of the Parotid Gland: A Case and Literature’s Review," International Journal of Otolaryngology and Head & Neck Surgery, Vol. 2 No. 6, 2013, pp. 232-235. doi: 10.4236/ijohns.2013.26048.


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