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Salivary Alpha-Amylase Reactivity under Psycho-Physiological Stress. A Nonverbal Communication Measurement Tool?

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DOI: 10.4236/jbbs.2011.11003    5,115 Downloads   11,099 Views   Citations

ABSTRACT

Previous studies have shown that changes in salivary alpha-amylase (sAA) levels are dependent on psychosocial stress stimulation and reflect the activity of the sympathetic nervous system. sAA measurement can be performed easily and quickly; therefore, it may be useful for evaluating psychosocial or physical stress. The aim of this preliminary study was to examine the use of sAA measurements as objective indicators of psychological and physiological stress levels by examining sAA changes in volunteers subjected to conditions similar to those suffered by children with severe motor and intellectual disabilities and cerebral paralysis. Twelve healthy volunteers were required to not move or speak, as is found in patients suffering from total paralysis, for 30 min. Saliva samples were taken at three points, and sAA activity was measured using a hand-held monitor before the test, immediately after the test, and 10 min after the test. In the present study, a marked increase in sAA activity due to physiological stress and a rapid return to the baseline level were observed. Many subjects felt bodily pain and psychotic discomfort. This measurement method is useful for evaluating stress in children with severe motor and intellectual disabilities, who can not fully express their emotions or communicate with their caregivers.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

T. Inagaki, M. Ieda, S. Yamashita, T. Miyaoka and J. Horiguchi, "Salivary Alpha-Amylase Reactivity under Psycho-Physiological Stress. A Nonverbal Communication Measurement Tool?," Journal of Behavioral and Brain Science, Vol. 1 No. 1, 2011, pp. 12-15. doi: 10.4236/jbbs.2011.11003.

References

[1] N. Takai, M. Yamaguchi, T. Aragaki, K Eto, K. Uchihashi and Y. Nishikawa, “Gender-specific Differences in Salivary Biomarker Responses to Acute Psychological Stress,” Annals of the New York Academy of Sciences, Vol. 1098, 2007, pp. 510-515. doi:10.1196/annals.1384.014
[2] E. B. Gordis, D. A. Granger, E. J. Susman and P. K. Trickett, “Asymmetry between Salivaly Cortisol and α-maylase Reactivity to Stress: Relation to Aggressive Behavior in Adolescents,” Psychoneuroendocrinology, Vol. 31, 2006, pp. 967-987. doi:10.1016/j.psyneuen.2006.05.010
[3] U. M. Nater and N. Rohlender, “Salivary Alpha-amylase as a Non-invasive Biomarker for the Sympathetic Ner- vous System: Current State of Research,” Psychoneuroendocrinology, Vol. 34, 2009, pp. 486-496. doi:10.1016/j.psyneuen.2009.01.014
[4] N. Rohlender, U. M. Nater, J. M. Wolf, U. Ehlert and C. Kirshbaum, “Psychosocial Stress-induced Activation of Salivary Alpha-amylase. An Indicator of Sympathetic Activity?” Annals of the New York Academy of Sciences, Vol. 1032, 2004, pp. 258-263. doi:10.1196/annals.1314.033
[5] S. Shirasaki, H. Fujii, M. Takahashi, T. Sato, M. Ebina, Y. Noto and K. Hirota, “Correlation between Salivary– Amylase Activity and Pain Scale in Patients with Chronic Pain,” Regional Anesthesia and Pain Medicine, Vol. 32, 2007, pp. 120-123.
[6] Y. Noto, T. Sato, M. Kudo, K. Kurata and K. Hirota, “The Relationship between Salivary Biomarkers and State Trait Anxiety Inventory Score under Mental Arithmetic Stress: A Pilot Study,” Anesthesia & Analgesia, Vol. 101, No. 6, 2005, pp. 1873-1876. doi:10.1213/01.ANE.0000184196.60838.8D
[7] U. M. Nater, N. Rohlender, J. Gaab, S. Berger, A. Jud, C. Kirshbaum and U. Ehlert, “Human Salivary Alpha-amylase Reactivity in a Psychosocial Paradigm,” International Journal of Psychophysiology, Vol. 55, No. 3, 2005, pp. 333-342. doi:10.1016/j.ijpsycho.2004.09.009
[8] U. M. Nater, R. L. Marca, L. Florin, A. Moses, W. Langhans, M. M. Koller and U. Ehlert, “Stress-induced Changes in Human Salivary Alpha-amylase Activity-associations with Adrenergic Activity,” Psychoneuroendocrinology, Vol. 31, 2006, pp. 49-58. doi:10.1016/j.psyneuen.2005.05.010
[9] A. van Stegeren, N. Rohleder, W. Everaerd and O. T. Wolf, “Salivary Alpha Amylase as Marker for Adrenergic Activity during Stress: Effect of Betablockade,” Psychoneuroendocrinology, Vol. 31, 2006, pp. 137-141. doi:10.1016/j.psyneuen.2005.05.012
[10] C. Grillon, R. Duncko, M. F. Covington, L. Kopperman and M. A. Kling, “Acute Stress Potentiates Anxiety in Humans,” Biological Psychiatry, Vol. 62, No. 10, 2007, pp. 1183-1186. doi:10.1016/j.biopsych.2007.06.007
[11] M. Yamaguchi, T. Kanemori, M. Kanemaru, N. Takai, Y. Mizuno and H. Yoshida, “Performance Evaluation of Salivary Amylase Activity Monitor,” Biosensors and Bioelectronics, Vol. 20, No. 3, 2004, pp. 491-497. doi:10.1016/j.bios.2004.02.012
[12] M. Yamaguchi, M. Deguchi, J. Wakasugi, S. Ono, N. Takai, T. Higashi and Y. Mizuno, “Hand-held Monitor of Sympathetic Nervous System Using Salivary Amylase Activity and Its Validation by Driver Fatigue Assessment,” Biosensors and Bioelectronics, Vol. 21, No. 7, 2006, pp. 1007-1014. doi:10.1016/j.bios.2005.03.014
[13] T. Higashi, Y. Mizuno, M. Oonishi, K. Takeda and M. Yamaguchi, “Nonverbal Communication Tool for Children with Severe Motor and Intellectual Disabilities Using Biochemical Measurement,” Conference Proceedings - IEEE Engineering in Medicine and Biology Society, Vol. 4, 2005, pp. 3538-3541.
[14] M. Yamaguchi, J. Wakasugi and J. Sakakima, “Competitive and Product Inhibition-based α-amylase Activity Analysis Method,” Clinical Biochemistry, Vol. 41, No. 4-5, 2008, pp. 325-330. doi:10.1016/j.clinbiochem.2007.10.016
[15] T. Inagaki, T. Miyaoka, S. Okazaki, H. Yasuda, T. kawamukai, E. Utani, R. Wake, M. Hayashida, J. Horiguchi and S. Tsuji, “High Salivary Alpha-amylase Levels in Patients with Schizophrenia: A Pilot Study,” Progress in Neuro-Psychopharamacology & Biological Psychiatry, Vol. 34, No. 4, 2010, pp. 688-691. doi:10.1016/j.pnpbp.2010.03.024

  
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