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The COP9 Signalosome Controls Adipocyte Differentiation by Regulating CHOP Protein Stability

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DOI: 10.4236/eng.2012.410B050    3,216 Downloads   3,930 Views  


Obesity is a serious health problem of our time. Dysfunction of adipogenesis, the differentiation of adipocytes, is a hallmark of obesity. Therefore here we investigate the role of the COP9 signalosome and of CHOP in the differentiation of LiSa-2 preadipocytes.

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The authors declare no conflicts of interest.

Cite this paper

X. Huang and W. Dubiel, "The COP9 Signalosome Controls Adipocyte Differentiation by Regulating CHOP Protein Stability," Engineering, Vol. 4 No. 10B, 2012, pp. 192-193. doi: 10.4236/eng.2012.410B050.


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