Urinary Schistosomiasis in Children—Still a Concern in Part of the Ghanaian Capital City


Schistosomiasis is a parasitic disease of the tropics which is estimated to affect up to 300 million people worldwide. While it is being successfully controlled in many countries, it remains a major public health problem, especially in developing countries including Ghana. Extensive work on schistosomiasis has been undertaken along theVoltaRiverbasin, leaving very little data and information on this infection in the urban and peri-urban areas inGhana. This study was aimed at determining the urinary schistosomiasis burden among children of school going age within Zenu, a suburb of the capital city. Urine samples were taken from 274 school children within the Zenu community and examined with urine chemistry dipsticks for detection and confirmation of haematuria, followed by microscopy for detection of Schistosoma haematobium ova. Prevalence of urinary schistosomiasis was 30.7% (95% CI: 25.2-36.2). 44 (52%) of the positive samples were collected from males whiles 40 (48%) were collected from females, but prevalence of the infection was not significantly associated with gender (χ2 = 0.041, DF = 1, P-Value = 0.839). Among the S. haematobium positive children, haematuria was detected by the dipstick in 88.1% (74/84, 95% CI: 81.2- 95.0), but it was not detected in 11.9% (10/84, 95% CI: 5.0-18.8). Meanwhile, the dipstick detected haematuria in 7.3% (20/274, 95% CI: 4.3-7.3) of the total population but microscopy could not detect the presence of Schistosoma ova in those children. An association was found between Schistosoma infection and haematuria detected by dipstick (χ2 = 84.715, DF = 1, P-Value < 0.001). It could be noted that urinary schistosomiasis in children is still a concern in parts of the Ghanaian capital city.

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P. Tetteh-Quarcoo, S. Attah, E. Donkor, M. Nyako, A. Minamor, E. Afutu, E. Hervie and P. Ayeh-Kumi, "Urinary Schistosomiasis in Children—Still a Concern in Part of the Ghanaian Capital City," Open Journal of Medical Microbiology, Vol. 3 No. 3, 2013, pp. 151-158. doi: 10.4236/ojmm.2013.33023.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] C. H. King, “Long-Term Outcomes of School-Based Treatment for Control of Urinary Schistosomiasis: A Review of Experience in Coast Province, Kenya,” Memórias do Instituto Oswaldo Cruz, Vol. 101, No. 1, 2006, pp. 299-306. doi:10.1590/S0074-02762006000900047
[2] A. Koukounari, A. F. Gabrielli, S. Touré, E. Bosqué-Oliva, Y. Zhang, B. Sellin, C. A. Donnelly, A. Fenwick and J. P. Webster, “Schistosoma haematobium Infection and Morbidity before and after Large-Scale Administration of Praziquantel in Burkina,” Journal of Infectious Diseases, Vol. 196, No. 5, 2007, pp. 659-669. doi:10.1086/520515
[3] N. Midzi, D. Sangweme, S. Zinyowera, M. P. Mapingure, K. C. Brouwer, N. Kumar, F. Mutapi, G. Woelk and T. Mduluza, “Efficacy and Side Effects of Praziquantel Treatment against Schistosoma haematobium Infection among Primary School Children in Zimbabwe,” Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 102, No. 8, 2008, pp. 759-766. doi:10.1016/j.trstmh.2008.03.010
[4] J. W. Rudge, J. R. Stothard, M. G. Basánez, A. F. Mgeni, I. S. Khamis, A. N. Khamis and D. Rollinson, “Micro-Epidemiology of Urinary Schistosomiasis in Zanzibar: Local Risk Factors Associated with Distribution of Infections among Schoolchildren and Relevance for Control,” Acta Tropica, Vol. 105, No. 1, 2008, pp. 45-54. doi:10.1016/j.actatropica.2007.09.006
[5] B. Gryseels, “The Relevance of Schistosomiasis for Public Health,” Tropical Medicine and Parasitology, Vol. 40, No. 2, 1989, pp. 134-142.
[6] M. G. Chen and K. E. Mott, “Progress in Assesment of Morbidity Due to Schistosoma haematobium Infection: A Review of Recent Literature,” Tropical Disease Bulletin, Vol. 86, No. 4, 1989, pp. R1-R36.
[7] A. W. Cheever, “Schistosomiasis and Neoplasia,” Journal of National Cancer Institute, Vol. 61, No. 1, 1978, pp. 13-18.
[8] D. M. Forsyth, D. J. Bradley and J. McMahon, “Death Attributed to Kidney Failure in Communities with Endemic Urinary Schistosomiasis,” Lancet, Vol. 2, No. 7670, 1970, pp. 472-473. doi:10.1016/S0140-6736(70)90095-4
[9] L. Chitsulo, D. Engels, A. Montresor and L. Savioli, “The Global Status of Schistosomiasis and Its Control,” Acta Tropica, Vol. 77, No. 1, 2000, pp. 41-51. doi:10.1016/S0001-706X(00)00122-4
[10] J. A. Patz, T. K. Graczyk, N. Geller and A. Y. Vittor, “Effects of Environmental Change on Emerging Parasitic Diseases,” International Journal for Parasitology, Vol. 30, No, 12, 2000, pp. 1395-1405. doi:10.1016/S0020-7519(00)00141-7
[11] K. Zakhary, “Factors Affecting the Prevalence of Schistosomiasis in the Volta Region of Ghana,” McGill Journal of Medicine, Vol. 3, 1997, pp. 93-101.
[12] D. Scott, K. Senker and E. C. England, “Epidemiology of Human Schistosoma haematobium Infection around Volta Lake, Ghana, 1973-75,” World Health Organization, Vol. 60, No. 1, 1982, pp. 89-100.
[13] R. Y.-T. Dzidzo, T. Annang, J. Otchere, D. Bentum, D. Edoh, C. Amoah and K. M. Bosompem, “Urinary Schistosomiasis among Adults in the Volta Basin of Ghana: Prevalence, Knowledge and Practices,” Journal of Tropical Medicine and Parasitology, Vol. 34, No. 1, 2011, pp. 1-16.
[14] www.sciencedirect.com
[15] M. J. van der Werf, K. M. Bosompem and S. J. de Vlas, “Schistosomiasis Control in Ghana: Case Management and Means for Diagnosis and Treatment within the Health System,” Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 97, No. 2, 2003, pp. 146-152. doi:10.1016/S0035-9203(03)90102-7
[16] P. Jordan, “From Katayama to the Dakhla Oasis: The Beginning of Epidemiology and Control of Bilharzia,” Acta Tropica, Vol. 77, No. 1, 2000, pp. 9-40. doi:10.1016/S0001-706X(00)00121-2
[17] G. R. Olds and S. Dasarathy, “Schistosomiasis,” Current Treatment Options in Infectious Diseases, Vol. 2, 2000, pp. 88-99.
[18] B. Gryseels, K. Polman, J. Clerinx and L. Kestens, “Human Schistosomiasis,” Lancet, Vol. 368, No. 9541, 2006, pp. 1106-1118. doi:10.1016/S0140-6736(06)69440-3
[19] H. M. Murare and P. Taylor, “Haematuria and Proteinuria during Schistosoma haematobium Infection: Relationship to Intensity of Infection and the Value of Chemical Reagent Strips for Pre- And Post-Treatment Diagnosis,” Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol. 81, No. 3, 1987, pp. 426-430. doi:10.1016/0035-9203(87)90158-1
[20] M. Cheesbrough, “District Laboratory Practice in Tropical Countries,” 2nd Edition, Cambridge University Press, Cambridge, 2005. doi:10.1017/CBO9780511581304
[21] S. El Katsha and S. Watts, “Gender, Behavior, and Health: Schistosomiasis Transmission and Control in Rural Egypt,” American University in Cairo Press, Cairo, 2002.
[22] A. Koukounari, J. P. Webster, C. A. Donnelly, B. C. Bray, J. Naples, K. Bosompem and C. Shiff, “Sensitivities and Specificities of Diagnostic Tests and Infection Prevalence of Schistosoma haematobium Estimated from Data on Adults in Villages Northwest of Accra, Ghana,” American Journal of Tropical Medicine and Hygiene, Vol. 80, No. 3, 2009, pp. 435-441.
[23] H. Feldmeier and G. Poggensee, “Diagnostic Techniques in Schistosomiasis Control: A Review,” Acta Tropica, Vol. 52, No. 4, 1993, pp. 205-220. doi:10.1016/0001-706X(93)90009-Z
[24] V. C. Tsang and P. P. Wilkins, “Immunodiagnosis of Schistosomiasis,” Immunological Investigations, Vol. 26, No. 1-2, 1997, pp. 175-188. doi:10.3109/08820139709048925
[25] A. Rabello, “Diagnosing Schistosomiasis,” Memórias do Instituto Oswaldo Cruz, Vol. 92, No. 5, 1997, pp. 669-676. doi:10.1590/S0074-02761997000500021
[26] A. P. Kapito-Tembo, V. Mwapasa, S. R. Meshnick, Y. Samanyika, D. Banda, C. Bowie and S. Radke, “Prevalence Distribution and Risk Factors for Schistosoma hematobium Infection among School Children in Blantyre, Malawi. PLoS Neglected Tropical Disease, Vol. 3, No. 1, 2009, p. e36. doi:10.1371/journal.pntd.0000361
[27] J. A. Patz, T. K. Graczyk, N. Geller and A. Y. Vittor, “Effects of Environmental Change on Emerging Parasitic Diseases,” International Journal for Parasitology, Vol. 30, No. 12, 2000, pp. 1395-1405. doi:10.1016/S0020-7519(00)00141-7
[28] H. A. Sackey, “The Determinants of School Attendance and Attainment in Ghana: A Gender Perspective,” African Economic Research Consortium, Vol. 173, 2007.
[29] J. R. Verani, B. Abudho, S. P. Montgomery, P. N. M. Mwinzi, H. L. Shane, S. E. Butler, D. M. S. Karanja and W. E. Secor, “Schistosomiasis among Young Children in Usoma, Kenya” American Journal of Tropical Medicine and Hygiene, Vol. 84, No. 5, 2011, pp. 787-791. doi:10.4269/ajtmh.2011.10-0685
[30] E. Doehring, “Schistosomiasis in Childhood,” European Journal of Pediatrics, Vol. 147, No. 1, 1988, pp. 2-9. doi:10.1007/BF00442602
[31] O. P. Nmorsi, N. C. Ukwandu, S. Ogoinja, H. O. Blackie and M. A. Odike, “Urinary Tract Pathology in Schistosoma haematobium Infected Rural Nigerians,” Southeast Asian Journal of Tropical Medicine and Public Health, Vol. 38, No. 1, 2007, pp. 32-37.

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