Rescuing experience of myasthenia gravis crisis (with 38 patients of clinical analysis)


Our research was designed to explore the more effective rescuing treatment by summarizing clinical features of the patients with myasthenia gravis crisis. During the course, we carried out a retrospective analysis about clinical data and the course of diagnose and treatment of 38 patients (65 cases) with myasthenia gravis crisis who were in hospital in recent 15 years. As a result, most patients with myasthenia gravis crisis relieved after positive treatment and the mortality was 3.1%. Among lots of treatments, incision of trachea earlier, hormonal therapy, dry treatment and to unite these three treatments were more effective than other treatments. The effective ratio was 100%. In the end, we concluded that to unite incision of trachea, immunosuppressive treatment and dry treatment reasonably can increase the effective ratio of rescuing myasthenia gravis crisis and improve the prognosis of patients obviously.

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Zhang, G. , Zhang, C. and Zeng, G. (2013) Rescuing experience of myasthenia gravis crisis (with 38 patients of clinical analysis). World Journal of Neuroscience, 3, 209-212. doi: 10.4236/wjns.2013.34027.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Feng, T.-Y. and Zhao, Y.-B. (2003) Myasthenia gravis diagnosis and treatment progress. Institute of Neurological Disorders and Stroke, 10, 190-191.
[2] Rowland, L.P. (1980) Controversies about the treatment of myasthenia gravis. Journal of Neurology, Neurosurgery & Psychiatry, 43, 644-659.
[3] Zhang, M., Yang, M.S. and Xu, J.Z. (2000) Immunotherapy of myasthenia gravis. Immunology and Nerve Chinese Journal of Neurology, 7, 237-241.
[4] Cong, Z.Q. (1994) Myasthenia gravis on the latest progress of the treatment. Practical Chinese Journal of Internal Medicine, 14, 326.
[5] Chen, L.E. and Zhang, C.G. (1992) Myasthenia gravis clinical analysis of 26 cases of crisis. Journal of China Institute of Neurological Disorders, 18, 360-361.
[6] Murthy, J.M., Meena, A.K., Chowdary, G.V. and Naryanan, J.T. (2005) Myasthenic crisis: Clinical features, complications and mortality. Neurology India, 23, 83-88.
[7] Thomas, C.E., Mayer, A.S., Gungor, Y., et al. (1997) Myasthenia gravis: Clinical feature, mortality, complications, and risk factors for prolonged intuition. Neurology, 48, 1253-1260.
[8] Zhang, C.G. and Chen, L.E. (1992) Myasthenia gravis crisis rescue experience. Journal of Clinical Neurology, 5, 92-94.
[9] Zhang, C.G., Chen, L.E. and Liu, W.B. (2001) The observation of efficacy and safety of day meal served prednisone treatment of myasthenia gravis. Journal of Clinical Neurology, 14, 240-241.
[10] Huang, Y.M. (1997) Immunology research of myasthenia gravis. Chinese Journal of Neurology, 30, 114-116.
[11] Xu, J.Z., Yang, M.S. and Li, B.H. (1999) 2385 cases of clinical research with myasthenia gravis. Chinese Journal of Neurology, 3, 347-350.
[12] Hahn, A.F. (2000) Intravenous immunoglobulin treatment in peripheral nerve disorder indications mechanisms of action and sideeffects. Current Opinion Neurology, 13, 575-582.
[13] Richman, D.P. and Agius, M.A. (2003) Treatment of autoimmune myasthenia gravis. Neurology, 61, 1652-1661.
[14] Richman, D.P. and Agius, M.A. (2003) Treatment principles in the management of autoimmune myasthenia gravis. Annals of the New York Academy of Sciences, 998, 457-472.
[15] Younqer, D.S. and Raksadawan, N. (2001) Medical therapies in myasthenia gravis. Chest Surgery Clinics of North America, 11, 329.
[16] Liu, C.C., Li, Z.L., Xian, S.M., et al. (2007) Care and emergency treatment of myasthenia gravis crisis. Chinese Journal of Practical Medicine, 2, 117-118.

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