Salen-Cu(II) Complex Catalyzed N-Arylation of Imidazoles under Mild Conditions


Three inexpensive and air-/moisture-stable Salen-Cu complexes 1-3 were evaluated to be a novel class of catalysts for the N-arylation of imidazoles with aryl halides. A variety of aryl iodides, bromides underwent the coupling with imida-zoles, promoted by the complex 3, in moderate to excellent yields without the protection by an inert gas.

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Y. Liu, Q. Zhang, X. Ma, P. Liu, J. Xie, B. Dai and Z. Liu, "Salen-Cu(II) Complex Catalyzed N-Arylation of Imidazoles under Mild Conditions," International Journal of Organic Chemistry, Vol. 3 No. 3, 2013, pp. 185-189. doi: 10.4236/ijoc.2013.33023.

Conflicts of Interest

The authors declare no conflicts of interest.


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