Quantification of Solid Residues by Raman Spectroscopy

Esau Araiza-Reyna, Roberto Sato-Berrú, América Vázquez-Olmos

Centro de Ciencias Aplicadas y Desarrollo Tecnológico, Universidad Nacional Autónoma de México, Circuito Exterior s/n, Ciudad Universitaria, Delegación Coyoacán, México D.F., México.
Facultad de Ciencias, Universidad Autónoma de San Luis Potosí, Av. Salvador Nava Martínez s/n, Zona Universitaria, San Luis Potosí, México.

DOI: 10.4236/opj.2013.35A001                

Abstract

We suggest a mathematical route which has the capability to obtain quantitative information of solid residues on a substrate of aluminum, in which the evaporation of the deposited micro-drops has the form of coffee rings. In this job, the glycine aminoacid was used as probe molecule. We suppose that the number of moles present on the study sample is proportional to the Raman signal and to the experimental parameters of the used Raman system. Then, the mass and the number of molecules can be determined with these data. We showed that the mathematical expression is simple and elegant for its implementation. On the other hand, we have applied and demonstrated that the technique of principal component analysis (PCA) can be used to obtain quantitative information of the sample. Our results show quantitative analysis of glycine residues between 10^-11 to 10^{-15 g.}

Keywords

Quantitative Raman; Aminoacids; Glycine; Solid residues; Drop Coating Deposition Raman; Principal Component Analysis

Conflicts of Interest

The authors declare no conflicts of interest.

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