Morphological substantiation of application of cellular technologies for correction of striae
Igor Maiborodin, Andrey Shevela, Andrey Babko, Vitaly Morozov, Vera Matveeva
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DOI: 10.4236/health.2010.212213   PDF    HTML     6,406 Downloads   11,371 Views   Citations

Abstract

The possibility of the application of autologic pluripotent cells from peripheral blood (APCPB) for correction of striae after pregnancy was studied. Visually first signs of improvement of atrophic scars can be noticed in 6-8 weeks after injection of APCPB and gradually progress during 6 months. The atrophy of epithelium, hyperkeratosis, sclerosis of all dermis layers with smoothing of papillae, reduction of number of blood vessels and skin appendages were found before treatment by method of light mi-croscopy. In all observations after injection of APCPB in a connective tissue, which replaces of dermis, an increase of number of vessels at the expense of processes of neoangiogenesis, leukocytic infiltration reduction, thinning and ordering of arrangement of collagen and elastin fibers were detected. These results give a chance for more successful application of cosmetology procedures for correction of these defects of skin.

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Maiborodin, I. , Shevela, A. , Babko, A. , Morozov, V. and Matveeva, V. (2010) Morphological substantiation of application of cellular technologies for correction of striae. Health, 2, 1430-1436. doi: 10.4236/health.2010.212213.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] D. J. Goldberg, E. S. Marmur, C. Schmults, M. Hussain and R. Phelps “Histologic and Ultrastructural Analysis of Ultraviolet B Laser and Light Source Treatment of Leukoderma in Striae Distensae,” Dermatologic Surgery, Vol. 31, No. 4, 2005, pp. 385-387.
[2] B. J. Kim, D. H. Lee, M. N. Kim, K. Y. Song, W. I. Cho, C. K. Lee, J. Y. Kim and O. S. Kwon “Fractional Photothermolysis for the Treatment of Striae Distensae in Asian Skin,” American Journal of Clinical Dermatology, Vol. 9, No. 1, 2008, pp. 33-37.
[3] Y. K. Tay, C. Kwok and E. Tan “Non-Ablative 1,450-nm Diode Laser Treatment of Striae Distensae,” Lasers in Surgery and Medicine, Vol. 38, No. 3, 2006, pp. 196-199.
[4] K. Nouri, R. Romagosa, T. Chartier, L. Bowes and J. M. Spencer “Comparison of the 585 nm Pulse Dye Laser and the Short Pulsed CO2 Laser in the Treatment of Striae Distensae in Skin Types IV and VI,” Dermatologic Surgery, Vol. 25, No. 5, 1999, pp. 368-370.
[5] T. Aoyama, U. Francke, C. Gasner and H. Furthmayr “Fibrillin Abnormalities and Prognosis in Marfan Syndrome and Related Disorders,” American Journal of Medical Genetics, Vol. 58, No. 2, 1995, pp. 169-176.
[6] K. S. Lee, Y. J. Rho, S. I. Jang, M. H. Suh and J. Y. Song “Decreased Expression of Collagen and Fibronectin Genes in Striae Distensae Tissue,” Clinical and Experimental Dermatology, Vol. 19, No. 4, 1994, pp. 285-288.
[7] S. Shuster “The Cause of Striae Distensae,” Acta Dermato-Venereologica. Supplementum (Stockh), Vol. 59, No. 85, 1979, pp. 161-169.
[8] C. Viennet, J. Bride, A. Cohen-Letessier and P. Humbert “Comportement Mecanique de Fibroblastes de Vergetures Inclus Dans des Lattices de Collagene,” Journal de la Societe de Biologie, Vol. 195, No. 4, 2001, pp. 427-430.
[9] C. Viennet, J. Bride, V. Armbruster, F. Aubin, A. C. Gabiot, T. Gharbi and P. Humbert “Contractile Forces Generated by Striae Distensae Fibroblasts Embedded in Collagen Lattices,” Archives of Dermatological Research, Vol. 297, No. 1, 2005, pp. 10-17.
[10] R. E. Watson, E. J. Parry, J. D. Humphries, C. J. Jones, D. W. Polson, C. M. Kielty and C. E. Griffiths “Fibrillin Microfibrils Are Reduced in Skin Exhibiting Striae Distensae,”. The British Journal of Dermatology, Vol. 138, No. 6, 1998, pp. 931-937.
[11] P. Girault, J. Waton, A. Barbaud, P. Bordigoni and J. Schmutz “Isomorphic Disposition of Chronic Graft- versus-Host Disease in Striae Distensae,” Journal of the European Academy of Dermatology and Venereology, Vol. 23, No. 5, 2009, pp. 574-575.
[12] H. M. Sheu, H. S. Yu and C. H. Chang “Mast Cell Degranulation and Elastolysis in the Early Stage of Striae Distensae,” Journal of Cutaneous Pathology, Vol. 18, No. 6, 1991, pp. 410-416.
[13] T. Tsuji and M. Sawabe “Elastic Fibers in Striae Distensae,” Journal of Cutaneous Pathology, Vol. 15, No. 4, 1988, pp. 215-222.
[14] P. Zheng, R. M. Lavker and A. M. Kligman “Anatomy of Striae,” The British Journal of Dermatology, Vol. 112, No. 2, 1985, pp. 185-193.
[15] G. Singh and L. P. Kumar “Striae Distensae,” Indian Journal of Dermatology, Venereology and Leprology, Vol. 71, No. 5, 2005, pp. 370-372.
[16] R. Tehrani “Microdermabrasion for Striae Distensae,” Indian Journal of Dermatology, Venereology and Leprology, Vol. 72, No. 1, 2006, pp. 59.
[17] M. de Buman, M. Walther and R. de Weck “Wirksamkeit der Alphastria-Creme bei der Vorbeugung von Schwangerschaftsstreifen,” Gynakologische Rundschau, Vol. 27, No. 2, 1987, pp. 79-84.
[18] M. Walther “Il Trattamento Preventivo Delle "Striae Distensae" Durante la Gravidanza,” Minerva Ginecologica, Vol. 33, No. 5, 1981, pp. 497-499.
[19] F. Wierrani, W. Kozak, W. Schramm and W. Grünberger “Versuch einer Vorbeugenden Behandlung der Striae Gravidarum Mittels Prophylaktischer Massagesalbenapplikation,” Wiener Klinische Wochenschrift, Vol. 104, No. 2, 1992, pp. 42-44.

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