Stable isotopes and body composition in children: History, fundamentals, and clinical applications
Wendell Costa Bila, Joel Alves Lamounier, André Everton de Freitas, Valmin Ramos Silva, Sylvia Dias Turani, José Eduardo Dutra de Oliveira
Faculty of Medicine, Federal University of S?o Jo?o Del Rei-West Campus Center, Divinópolis, Brazil.
Faculty of Medicine, School of Sciences of Santa Casa de Misericordia of Vitoria, Nossa Senhora da Glória Children’s Hospital, Vitória, Brazil.
Faculty of Medicine, University of S?o Paulo-Ribeir?o Preto, Brazil.
Graduate Program in Child and Teenager Health-Medicine School-UFMG Belo Horizonte, College of Health and Human Ecology-FASEH Vespasiano, Brazil.
Graduate Program in Health Sciences, Federal University of S?o Jo?o Del Rei-West Campus Center, Divinópolis, Brazil;.
DOI: 10.4236/health.2013.58A3009   PDF   HTML     4,795 Downloads   7,116 Views   Citations


The aim of this study was to gather information on the use of stable isotopes to measure total body water and body composition scan in children. We selected studies in the last 13 years, in addition to classical studies on the subject, indexed in the database PubMed, LILACS, BVS and SciELO. The body composition was characterized by the amount of bone tissue, muscle and adipose tissue, also including the organs as well as levels of body water. Your knowledge becomes increasingly important in light of the changes that occur in the nutritional status of various types of diseases in frameworks, such as diabetes mellitus, protein energy malnutrition, in cases of obesity and metabolic syndrome. The ability to accurately assess body fat mass especially in children is associated with the importance of effective strategies for prevention and treatment of childhood obesity. Historically, in addition to clinical applications, measurements of total body water were used to determine body composition in nutritional studies. To the knowledge of the body composition, the body water can be measured and used by the ingestion of a dose of labeled water. The measured isotope enrichment is a function of the amount of body water. The method of deuterium is particularly interesting for the assessment of body composition in children, due to its characteristics of collection and analysis.

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Bila, W. , Lamounier, J. , Freitas, A. , Silva, V. , Turani, S. and de Oliveira, J. (2013) Stable isotopes and body composition in children: History, fundamentals, and clinical applications. Health, 5, 61-68. doi: 10.4236/health.2013.58A3009.

Conflicts of Interest

The authors declare no conflicts of interest.


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