|
[1]
|
M. Scharl and G. Rogler, “Inflammatory Bowel Disease: Dysfunction of Autophagy?” Digestive Disease, Vol. 30, No. 3, 2012, pp. 12-19. doi:10.1159/000342588
|
|
[2]
|
S. Danese and A. Mantovani, “Inflammatory Bowel Disease and Intestinal Cancer: A Paradigm of the Yin-Yang Interplay between Inflammation and Cancer,” Oncogene, Vol. 29, No. 23, 2010, pp. 3313-3323.
doi:10.1038/onc.2010.109
|
|
[3]
|
M. Rutter, B. Saunders, K. Wilkinson, S. Rumbles, G. Schofield, M. Kamm, C. Williams, A. Price, I. Talbot and A. Forbes, “Severity of Inflammation Is a Risk Factor for Colorectal Neoplasia in Ulcerative Colitis,” Gastroenterology, Vol. 126, No. 2, 2004, pp. 451-460.
doi:10.1053/j.gastro.2003.11.010
|
|
[4]
|
J. A. Eaden, K. R. Abrams and J. F. Mayberry, “The Risk of Colorectal Cancer in Ulcerative Colitis: A Meta-Analysis,” Gut, Vol. 48, No. 4, 2001, pp. 536-535.
doi:10.1136/gut.48.4.526
|
|
[5]
|
M. D. Rutter, B. P. Saunders, K. H. Wilkinson, S. Rumbles, G. Schofield, M. A. Kamm, C. B. Williams, A. B. Price, I. C. Talbot and A. Forbes, “Thirty-Year Analysis of a Colonoscopic Surveillance Program for Neoplasia in Ulcerative Colitis,” Gastroenterology, Vol. 130, No. 4, 2006, pp. 1030-1038. doi:10.1053/j.gastro.2005.12.035
|
|
[6]
|
A. Ekbom, M. Zack and H. O. Adami, “The Epidemiology of Inflammatory Bowel Disease: A Large, PopulationBased Study in Sweden,” Gastroenterology, Vol. 100, No. 2, 1991, pp. 350-358.
|
|
[7]
|
S. I. Grivennikov, “Inflammation and Colorectal Cancer: Colitis-Associated Neoplasia,” Seminars in Immunopathology, Vol. 35, No. 2, 2013, pp. 229-244.
doi:10.1007/s00281-012-0352-6
|
|
[8]
|
H. S. Cooper, S. Murthy, K. Kido, H. Yoshitake and A. Flanigan, “Dysplasia and Cancer in the Dextran Sulfate Sodium Mouse Colitis Model. Relevance to Colitis-Associated Neoplasia in the Human: A Study of Histopathology, B-Catenin and p53 Expression and the Role of Inflammation,” Carcinogenesis, Vol. 21, No. 4, 2000, pp. 757-768. doi:10.1093/carcin/21.4.757
|
|
[9]
|
R. L. Shattuck-Brandt, G. W. Varilek, A. Radhika, F. Yang, M. K. Washington and R. N. DuBois, “Cyclooxygenase 2 Expression Is Increased in the Stroma of Colon Carcinomas from IL-10(-/-) Mice,” Gastroenterology, Vol. 118, No. 2, 2000, pp. 337-345.
doi:10.1016/S0016-5085(00)70216-2
|
|
[10]
|
P. Sansone, G. Piazzi, P. Paterini, A. Strillacci, C. Ceccarelli, F. Minni, G. Biasco, P. Chieco and M. Bonafè, “Cyclooxygenase-2/Carbonic Anhydrase-IX Up-Regulation Promotes Invasive Potential and Hypoxia Survival in Colorectal Cancer Cells,” Journal of Cellular and Molecular Medicine, Vol. 13, No. 9, 2009, pp. 3876-3887.
doi:10.1111/j.1582-4934.2008.00580.x
|
|
[11]
|
K. Nys and S. Vermeire, “Autophagy: A New Target or an Old Strategy for the Treatment of Crohn’s Disease?” Nature Reviews Gastroenterology & Hepatology, 2013, in Press.
|
|
[12]
|
B. Bonaz, C. Picq, V. Sinniger, J. F. Mayol and D. Clarencon, “Vagus Nerve Stimulation: From Epilepsy to the Cholinergic Anti-Inflammatory Pathway,” Neurogastroenterology & Motility, Vol. 25, No. 3, 2013, pp. 208-221.
doi:10.1111/nmo.12076
|
|
[13]
|
C. Cheyuo, A. Jacob, R. Wu, M. Zhou, G. F. Coppa and P. Wang, “The Parasympathetic Nervous System in the Quest for Stroke Therapeutics,” Journal of Cerebral Blood Flow & Metabolism, Vol. 31, 2011, pp. 1187-1195.
doi:10.1038/jcbfm.2011.24
|
|
[14]
|
V. A. Pavlov and K. J. Tracey, “The Cholinergic AntiInflammatory Pathway,” Brain, Behavior, and Immunity, Vol. 19, No. 6, 2005, pp. 493-499.
|
|
[15]
|
L. V. Borovikova, M. Zhang, H. Yang, G. I. Botchkina, L. R. Watkins, H. Wang, N. Abumrad, J. W. Eaton and K. J. Tracey, “Vagus Nerve Stimulation Attenuates the Systemic Inflammatory Response to Endotoxin,” Nature, Vol. 405, No. 6785, 2000, pp. 458-462.
doi:10.1038/35013070
|
|
[16]
|
H. Wang, M. Yu, M. Ochani, C. A. Amella, M. Tanovic, S. Susarla, J. H. Li, H. Wang, H. Yang, L. Ulloa, Y. AlAbed, C. J. Czura and K. J. Tracey, “Nicotinic Acetylcholine Receptor Alpha7 Subunit Is an Essential Regulator of Inflammation,” Nature, Vol. 421, No. 6921, 2003, pp. 384-388. doi:10.1038/nature01339
|
|
[17]
|
K. J. Tracey, “The Inflammatory Reflex,” Nature, Vol. 420, No. 6917, 2002, pp. 853-859.
doi:10.1038/nature01321
|
|
[18]
|
K. J. Tracey, “Physiology and Immunology of the Cholinergic Antiinflammatory Pathway,” Journal of Clinical Investigation, Vol. 117, No. 2, 2007, pp. 289-296.
doi:10.1172/JCI30555
|
|
[19]
|
A. Miyazawa and N. Unwin, “Structure and Gating Mechanism of the Acetylcholine Receptor Pore,” Nature, Vol. 423, No. 6943, 2003, pp. 949-955.
doi:10.1038/nature01748
|
|
[20]
|
J. Wess, “Molecular Biology of Muscarinic Acetylcholine Receptors,” Critical Reviews in Neurobiology, Vol. 10, No. 1, 1996, pp. 69-99.
doi:10.1615/CritRevNeurobiol.v10.i1.40
|
|
[21]
|
L. G. Paleari, A. Cesario and P. Russo, “The Cholinergic System and Cancer,” Seminars in Cancer Biology, Vol. 18, No. 3, 2008, pp. 211-217.
doi:10.1016/j.semcancer.2007.12.009
|
|
[22]
|
M. Sopori, “Effects of Cigarette Smoke on the Immune System,” Nature Reviews Immunology, Vol. 2, No. 5, 2002, pp. 372-377. doi:10.1038/nri803
|
|
[23]
|
C. J. Czura, S. G. Friedman and K. J. Tracey, “Neural Inhibition of Inflammation: The Cholinergic Anti-Inflammatory Pathway,” Journal of Endotoxin Research, Vol. 9, No. 6, 2003, pp. 409-413.
|
|
[24]
|
L. Ulloa, “The Vagus Nerve and the Nicotinic Anti-Inflammatory Pathway,” Nature Reviews Drug Discovery, Vol. 4, No. 8, 2005, pp. 673-684. doi:10.1038/nrd1797
|
|
[25]
|
H. M. Schuller, “Nitrosamines as Nicotinic Receptor Ligands,” Life Sciences, Vol. 80, No. 24-25, 2007, pp. 2274-2280. doi:10.1016/j.lfs.2007.03.006
|
|
[26]
|
D. J. van Westerloo, I. A. Giebelen, S. Florquin, M. J. Bruno, G. J. Larosa, L. Ulloa, K. J. Tracey and T. van der Poll, “The Vagus Nerve and Nicotinic Receptors Modulate Experimental Pancreatitis Severity in Mice,” Gastroenterology, Vol. 130, No. 6, 2006, pp. 1822-1830.
doi:10.1053/j.gastro.2006.02.022
|
|
[27]
|
J. E. Ghia, P. Blennerhassett, H. Kumar-Ondiveeran, E. F. Verdu and S. M. Collins, “The Vagus Nerve: A Tonic Inhibitory Influence Associated with Inflammatory Bowel Disease in a Murine Model,” Gastroenterology, Vol. 131, No. 4, 2006, pp. 1122-1130.
doi:10.1053/j.gastro.2006.08.016
|
|
[28]
|
J. Meregnani, D. C, M. Vivier, A. Peinnequin, C. Mouret, V. Sinniger, C. Picq, A. Job, F. Canini, M. Jacquier-Sarlin and B. Bonaz, “Anti-Inflammatory Effect of Vagus Nerve Stimulation in a Rat Model of Inflammatory Bowel Disease,” Autonomic Neuroscience: Basic and Clinical, Vol. 160, No. 1, 2011, pp. 82-89.
doi:10.1016/j.autneu.2010.10.007
|
|
[29]
|
F. The, C. Cailotto, J. van der Vliet, W. J. de Jonge, R. J. Bennink, R. M. Buijs and G. E. Boeckxstaens, “Central Activation of the Cholinergic Anti-Inflammatory Pathway Reduces Surgical Inflammation in Experimental PostOperative Ileus,” British Journal of Pharmacology, Vol. 163, No. 5, 2011, pp. 1007-1016.
doi:10.1111/j.1476-5381.2011.01296.x
|
|
[30]
|
A. H. Milby, C. H. Halpern and G. H. Baltuch, “Vagus Nerve Stimulation for Epilepsy and Depression,” Neurotherapeutics, Vol. 5, No. 1, 2008, pp. 75-85.
doi:10.1016/j.nurt.2007.10.071
|
|
[31]
|
V. A. Pavlov and K. J. Tracey, “The Vagus Nerve and the Inflammatory Reflex—Linking Immunity and Metabolism,” Nature Reviews Endocrinology, Vol. 8, 2012, pp. 743-754. doi:10.1038/nren do.2012.189
|
|
[32]
|
S. P. Hussain, L. J. Hofseth and C. C. Harris, “Radical Causes of Cancer,” Nature Reviews Cancer, Vol. 3, No. 6, 2003, pp. 267-285. doi:10.1038/nrc1046
|
|
[33]
|
G. K. Zupanc, I. Horschke and D. A. Lovejoy, “Corticotropin Releasing Factor in the BRain of the Gymnotiform Fish, Apteronotus leptorhynchus: Immunohistochemical Studies Combined with Neuronal Tract Tracing,” General and Comparative Endocrinology, Vol. 114, No. 3, 1999, pp. 349-364.doi:10.1006/gcen.1999.7273
|
|
[34]
|
P. M. O’Connor, T. K. Lapointe, P. L. Beck and A. G. Buret, “Mechanisms by Which Inflammation May Increase Intestinal Cancer Risk in Inflammatory Bowel Disease,” Inflammatory Bowel Diseases, Vol. 16, No. 8, 2010, pp. 1411-1420. doi:10.1002/ibd.21217
|
|
[35]
|
J. Terzi?, S. Grivennikov, E. Karin and M. Karin, “Inflammation and Colon Cancer,” Gastroenterology, Vol. 138, No. 6, 2010, pp. 2101-2114.
|
|
[36]
|
O. M. Kalashnyk, G. L. Gergalova, S. V. Komisarenko and M. V. Skok, “Intracellular Localization of Nicotinic Acetylcholine Receptors in Human Cell Lines,” Life Sciences, Vol. 91, No. 21-22, 2012, pp. 1033-1037.
doi:10.1016/j.lfs.2012.02.005
|
|
[37]
|
C. L. Hirota and D. M. McKay, “Cholinergic Regulation of Epithelial Ion Transport in the Mammalian Intestine,” British Journal of Pharmacology, Vol. 149, No. 5, 2006, pp. 463-479. doi:10.1038/sj.bjp.0706889
|
|
[38]
|
R. Kopp, G. Lambrecht, E. Mutschler, U. Moser, R. Tacke and A. Pfeiffer, “Human HT-29 Colon Carcinoma Cells Contain Muscarinic M3 Receptors Coupled to Phosphoinositide Metabolism,” European Journal of Pharmacology: Molecular Pharmacology, Vol. 172, No. 4-5, 1989, pp. 397-405. doi:10.1016/0922-4106(89)90021-7
|
|
[39]
|
K. E. J. Dickinsona, R. A. Frizzellb and M. C. Sekar, “Activation of T84 Cell Chloride Channels by Carbachol Involves a Phosphoinositide-Coupled Muscarinic M3 Receptor,” European Journal of Pharmacology: Molecular Pharmacology, Vol. 225, No. 4, 1992, pp. 291-298.
doi:10.1016/0922-4106(92)90102-2
|
|
[40]
|
K. E. O’Malley, C. B. Farrell, K. M. O’Boyle and A. W. Baird, “Cholinergic Activation of Cl-Secretion in Rat Colonic Epithelia,” European Journal of Pharmacology, Vol. 275, No. 1, 1995, pp. 83-89.
|
|
[41]
|
P. Simon-Assmann, M. Kedinger, A. De Arcangelis, V. Rousseau and P. Simo, “Extracellular Matrix Components in Intestinal Development,” Experientia, Vol. 51, No. 9-10, 1995, pp. 883-900. doi:10.1007/BF01921739
|
|
[42]
|
M. Aumailley and T. Krieg, “Laminins: A Family of Diverse Multifunctional Molecules of Basement Membranes,” Journal of Investigative Dermatology, Vol. 106, No. 2, 1996, pp. 209-214.
doi:10.1111/1523-1747.ep12340471
|
|
[43]
|
J.-F. Beaulieu, “Extracellular Matrix Components and Integrins in Relationship to Human Intestinal Epithelial Cell Differentiation,” Progress in Histochemistry and Cytochemistry, Vol. 31, No. 4, 1997, pp. 1-76.
doi:10.1016/S0079-6336(97)80001-0
|
|
[44]
|
S. Miyamoto, S. K. Akiyama and K. M. Yamada, “Synergistic Roles for Receptor Occupancy and Aggregation in Integrin Transmembrane Function,” Science, Vol. 267, No. 5199, 1995, pp. 883-885.
doi:10.1126/science.7846531
|
|
[45]
|
M. A. Schwartz, M. D. Schaller and M. H. Ginsberg, “Integrins: Emerging Paradigms of Signal Transduction,” Annual Review of Cell and Developmental Biology, Vol. 11, No. 1, 1995, pp. 549-599.
doi:10.1146/annurev.cb.11.110195.003001
|
|
[46]
|
Z. Hossain and T. Hirata, “Molecular Mechanism of Intestinal Permeability: Interaction at Tight Junctions,” Molecular BioSystems, Vol. 4, No. 12, 2008, pp. 1181-1185.
doi:10.1039/b800402a
|
|
[47]
|
C. M. Niessen, “Tight Junctions/Adherens Junctions: Basic Structure and Function,” Journal of Investigative Dermatology, Vol. 127, 2007, pp. 2535-2532.
doi:10.1038/sj.jid.5700865
|
|
[48]
|
J. A. Jankowski, F. K. Bedford and Y. S. Kim, “Changes in Gene Structure and Regulation of E-Cadherin during Epithelial Development, Differentiation, and Disease,” Progress in Nucleic Acid Research and Molecular Biology, Vol. 57, 1997, pp. 187-215.
doi:10.1016/S0079-6603(08)60281-0
|
|
[49]
|
A. Zweibaum, M. Pinto, G. Chevalier, E. Dussaulx, N. Triadou, B. Lacroix, K. Haffen, J.-L. Brun and M. Rousset, “Enterocytic Differentiation of a Subpopulation of the Human Colon Tumor Cell Line HT-29 Selected for Growth in Sugar-Free Medium and Its Inhibition by Glucose,” Journal of Cellular Physiology, Vol. 122, No. 1, 1985, pp. 27-29. doi:10.1002/jcp.1041220105
|
|
[50]
|
N. T. Chartier, M. Laine, S. Gout, G. Pawlak, C. A. Marie, P. Matos, et al., “Laminin-5-Integrin Interaction Signals through PI 3-Kinase and Rac1b to Promote Assembly of Adherens Junctions in HT-29 Cells,” Journal of Cell Science, Vol. 119, 2006, pp. 31-46. doi:10.1242/jcs.02698
|
|
[51]
|
E. A. Wayner, S. G. Gil, G. F. Murphy, M. S. Wilke and W. G. Carter, “Epiligrin, a Component of Epithelial Basement Membranes, Is an Adhesive Ligand for Alpha 3 Beta 1 Positive T Lymphocytes,” The Journal of Cell Biology, Vol. 121, No. 5, 1993, pp. 1141-1152.
doi:10.1083/jcb.121.5.1141
|
|
[52]
|
J. B. Weitzman, R. Pasqualini, Y. Takada and M. E. Hemler, “The Function and Distinctive Regulation of the Integrin VLA-3 in Cell Adhesion, Spreading, and Homotypic Cell Aggregation,” The Journal of Biological Chemistry, Vol. 268, No. 12, 1993, pp. 8651-8657.
|
|
[53]
|
A. E. Summers, C. J. Whelan and M. E. Parsons, “Nicotinic Acetylcholine Receptor Subunits and Receptor Activity in the Epithelial Cell Line HT29,” Life Sciences, Vol. 72, No. 18-19, 2003, pp. 2091-2094.
doi:10.1016/S0024-3205(03)00089-4
|
|
[54]
|
C. Huet, C. Sahuquillo-Merino, E. Coudrier and D. Louvard, “Absorptive and Mucus-Secreting Subclones Isolated from a Multipotent Intestinal Cell Line (HT-29) Provide New Models for Cell Polarity and Terminal Differentiation,” The Journal of Cell Biology, Vol. 105, No. 1, 1987, pp. 345-357. doi:10.1083/jcb.105.1.345
|
|
[55]
|
S. P. Gout, M. R. Jacquier-Sarlin, L. Rouard-Talbot, P. Rousselle and M. R. Block, “RhoA-Dependent Switch between Alpha2Beta1 and Alpha3Beta1 Integrins Is Induced by Laminin-5 during Early Stage of HT-29 Cell Differentiation,” Molecular Biology of the Cell, Vol. 12, No. 10, 2001, pp. 3268-3281.
|
|
[56]
|
S. Gout, C. Marie, M. Lainé, G. Tavernier, M. R. Block and M. Jacquier-Sarlin, “Early Enterocytic Differentiation of HT-29 Cells: Biochemical Changes and Strength Increases of Adherens Junctions,” Experimental Cell Research, Vol. 299, No. 2, 2004, pp. 498-510.
doi:10.1016/j.yexcr.2004.06.008
|
|
[57]
|
J. Fogh, “Human Tumor Cells in Vitro,” Plenum Press, New York, 1975, pp. 115-141.
|
|
[58]
|
H. P. S. Wong, L. Yu, E. K. Y. Lam, E. K. K. Tai, W. K. K. Wu and C. H. Cho, “Nicotine Promotes Cell Proliferation via Alpha7-Nicotinic Acetylcholine Receptor and Catecholamine-Synthesizing Enzymes-Mediated Pathway in Human Colon Adenocarcinoma HT-29 Cells,” Toxicology and Applied Pharmacology, Vol. 221, No. 3, 2007, pp. 261-267. doi:10.1016/j.taap.2007.04.002
|
|
[59]
|
A. Pettersson, L. Nilsson, G. Nylund, A. KhorramManesh, S. Nordgren and D. S. Delbro, “Is Acetylcholine an Autocrine/Paracrine Growth Factor via the Nicotinic Alpha7-Receptor Subtype in the Human Colon Cancer Cell Line HT-29?” European Journal of Pharmacology, Vol. 609, No. 1-3, 2009, pp. 27-33.
doi:10.1016/j.ejphar.2009.03.002
|
|
[60]
|
C. D’Souza-Schorey, “Disassembling Adherens Junctions: Breaking Up Is Hard to Do,” Trends in Cell Biology, Vol. 15, No. 1, 2005, pp. 19-26. doi:10.1016/j.tcb.2004.11.002
|
|
[61]
|
S. Razani-Boroujerdi, M. Behl, F. F. Hahn, J. C. PenaPhilippides, J. Hutt and M. L. Sopori, “Role of Muscarinic Receptors in the Regulation of Immune and Inflammatory Responses,” Journal of Neuroimmunology, Vol. 194, No. 1, 2008, pp. 83-88.
doi:10.1016/j.jneuroim.2007.11.019
|
|
[62]
|
I. Wessler, C. J. Kirkpatrick and K. Racké, “Non-Neuronal Acetylcholine, a Locally Acting Molecule, Widely Distributed in Biological Systems: Expression and Function in Humans,” Pharmacology & Therapeutics, Vol. 77, No. 1, 1998, pp. 59-79.
doi:10.1016/S0163-7258(97)00085-5
|
|
[63]
|
T. Okuda and T. Haga, “High-Affinity Choline Transporter,” Neurochemical Research, Vol. 28, No. 3-4, 2003, pp. 483-488. doi:10.1023/A:1022809003997
|
|
[64]
|
K. Racké, U. R. Juergens and S. Matthiesen, “Control by Cholinergic Mechanisms,” European Journal of Pharmacology, Vol. 533, No. 1-3, 2006, pp. 57-68.
doi:10.1016/j.ejphar.2005.12.050
|
|
[65]
|
I. Wessler and C. J. Kirkpatrick, “Acetylcholine beyond Neurons: The Non-Neuronal Cholinergic System in Humans,” British Journal of Pharmacology, Vol. 154, No. 8, 2008, pp. 1558-1571. doi:10.1038/bjp.2008.185
|
|
[66]
|
M. F. Montenegro, F. Ruiz-Espejo, F. J. Campoy, E. Mu?oz-Delgado, M. Páez de la Cadena, F. J. RodríguezBerrocal and C. J. Vidal, “Cholinesterases Are DownExpressed in Human Colorectal Carcinoma,” Cellular and Molecular Life Sciences, Vol. 63, No. 18, 2006, pp. 2175-2182. doi:10.1007/s00018-006-6231-3
|
|
[67]
|
K. R. Cheng, R. Samimi, G. F. Xie, J. Shant, C. Drachenberg, M. Wade, R. J. Davis, G. Nomikos and J.-P. Raufman, “Acetylcholine Release by Human Colon Cancer Cells Mediates Autocrine Stimulation of Cell Proliferation,” American Journal of Physiology-Gastrointestinal and Liver Physiology, Vol. 295, No. 3, 2008, pp. G591-G597. doi:10.1152/ajpgi.00055.2008
|
|
[68]
|
I. Wessler, T. Reinheimer, H. Klapproth, F.-J. Schneider, K. Racké and R. Hammer, “Mammalian Glial Cells in Culture Synthesize Acetylcholine,” Naunyn-Schmiedeberg’s Archives of Pharmacology, Vol. 356, No. 5, 1997, pp. 694-697. doi:10.1007/PL00005107
|
|
[69]
|
J.-P. Raufman, R. Samimi, N. Shah, S. Khurana, J. Shant, C. Drachenberg, G. F. Xie, J. Wess and K. R. Cheng, “Genetic Ablation of M3 Muscarinic Receptors Attenuates Murine Colon Epithelial Cell Proliferation and Neoplasia,” Cancer Research, Vol. 68, 2008, pp. 3573-3578.
doi:10.1158/0008-5472.CAN-07-6810
|
|
[70]
|
H. Frucht, R. T. Jensen, D. Dexter, W. L. Yang and Y. Xiao, “Human Colon Cancer Cell Proliferation Mediated by the M3 Muscarinic Cholinergic Receptor,” Clinical Cancer Research, Vol. 5, No. 9, 1999, pp. 2532-2539.
|
|
[71]
|
W.-L. Yang and H. Frucht, “Cholinergic Receptor UpRegulates COX-2 Expression and Prostaglandin E(2) Production in Colon Cancer cells,” Carcinogenesis, Vol. 21, No. 10, 2000, pp. 1789-1793.
doi:10.1093/carcin/21.10.1789
|
|
[72]
|
C. W. Emala, J. Clancy and C. A. Hirshman, “Glucocorticoid Treatment Decreases Muscarinic Receptor Expression in Canine Airway Smooth Muscle,” American Journal of Physiology, Vol. 272, No. 4, 1997, pp. L745-L751.
|
|
[73]
|
D. B. Jacoby, B. L. Yost, B. Kumaravel, Y. Chan-Li, H.-Q. Xiao, K. Kawashima and A. D. Fryer, “Glucocorticoid Treatment Increases Inhibitory M(2) Muscarinic Receptor Expression and Function in the Airways,” American Journal of Respiratory Cell and Molecular Biology, Vol. 24, No. 4, 2001, pp. 485-91.
doi:10.1165/ajrcmb.24.4.4379
|
|
[74]
|
H. M. Schuller, “Cell Type Specific, Receptor-Mediated Modulation of Growth Kinetics in Human Lung Cancer Cell Lines by Nicotine and Tobacco-Related Nitrosamines,” Biochemical Pharmacology, Vol. 38, No. 20, 1989, pp. 3439-3442. doi:10.1016/0006-2952(89)90112-3
|
|
[75]
|
C. Gotti and F. Clementi, “Neuronal Nicotinic Receptors: From Structure to Pathology,” Progress in Neurobiology, Vol. 74, No. 6, 2004, pp. 363-396.
doi:10.1016/j.pneurobio.2004.09.006
|
|
[76]
|
Russo P CA, Cardinale A., “Presentation to the Special Issue: ‘α7-Nicotinic Receptor (α7-nAChR): One Target Different Diseases’,” Current Drug Targets, Vol. 13, No. , 2012, 573.
|
|
[77]
|
J.-P. Raufman, J. Shant, G. F. Xie, K. R. Cheng, X.-M. Gao, B. Shiu, N. Shah, C. B. Drachenberg, J. Heath, J. Wess and S. Khurana, “Muscarinic Receptor Subtype-3 Gene Ablation and Scopolamine Butylbromide Treatment Attenuate Small Intestinal Neoplasia in Apcmin/+ Mice,” Carcinogenesis, Vol. 32, No. 9, 2011, pp. 1396-1402.
doi:10.1093/carcin/bgr118
|
|
[78]
|
A. Belo, K. R. Cheng, A. Chahdi, J. Shant, G. F. Xie, S. Khurana and J.-P. Raufman, “Muscarinic Receptor Agonists Stimulate Human Colon Cancer Cell Migration and Invasion,” American Journal of Physiology-Gastrointestinal and Liver Physiology, Vol. 300, No. 5, 2011, pp. G749-G760. doi:10.1152/ajpgi.00306.2010
|
|
[79]
|
K. Cheng, P. Zimniak and J. P. Raufman, “Transactivation of the Epidermal Growth Factor Receptor Mediates Cholinergic Agonist-Induced Proliferation of H508 Human Colon Cancer Cells,” Cancer Research, Vol. 63, No. 20, 2003, pp. 6744-6750.
|
|
[80]
|
H. L. Cameron and M. H. Perdue, “Muscarinic Acetylcholine Receptor Activation Increases Transcellular Transport of Macromolecules across Mouse and Human Intestinal Epithelium in Vitro,” Neurogastroenterology & Motility, Vol. 19, No. 1, 2007, pp. 47-56.
doi:10.1111/j.1365-2982.2006.00845.x
|
|
[81]
|
V. T. Nguyena, J. Arredondoa, A. I. Chernyavskya, Y. Kitajimab and S. A. Grando, “Keratinocyte Acetylcholine Receptors Regulate Cell Adhesion,” Life Sciences, Vol. 72, No. 18-19, 2003, pp. 2081-2085.
doi:10.1016/S0024-3205(03)00087-0
|
|
[82]
|
Nguyen VT AJ, Chernyavsky AI, Kitajima Y, Pittelkow M, Grando SA., “Pemphigus Vulgaris IgG and Methylprednisolone Exhibit Reciprocal Effects on Keratinocytes,” The Journal of Biological Chemistry, Vol. 279, 2004, pp. 2135-2146. doi:10.1074/jbc.M309000200
|
|
[83]
|
S. Alemà and A. M. Salvatore, “p120 Catenin and Phosphorylation: Mechanisms and Traits of an Unresolved Issue,” Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, Vol. 1773, No. 1, 2007, pp. 47-58.
doi:10.1016/j.bbamcr.2006.06.001
|
|
[84]
|
E. Calautti, M. Grossi, C. Mammucari, Y. Aoyama, M. Pirro, Y. Ono, J. Li and G. P. Dotto, “Fyn Tyrosine Kinase Is a Downstream Mediator of Rho/PRK2 Function in Keratinocyte Cell-Cell Adhesion,” The Journal of Cell Biology, Vol. 156, No. 1, 2002, pp. 137-148.
doi:10.1083/jcb.200105140
|
|
[85]
|
J. Lilien, J. Balsamo, C. Arregui and G. Xu, “Turn-Off, Drop-Out: Functional State Switching of Cadherins,” Developmental Dynamics, Vol. 224, No. 1, 2002, pp. 18-29. doi:10.1002/dvdy.10087
|
|
[86]
|
M. Serresa, O. Filholb, H. Lickertc, C. Grangeassed, E. M. Chambazb, J. Stappertc, C. Vincenta and D. Schmitt, “The Disruption of Adherens Junctions Is Associated with a Decrease of E-Cadherin Phosphorylation by Protein Kinase CK2,” Experimental Cell Research, Vol. 15, No. 2, 2000, pp. 255-264.
doi:10.1006/excr.2000.4895
|
|
[87]
|
S. Dupre-Crochet, A. Figueroa, C. Hogan, E. C. Ferber, C. U. Bialucha, J. Adams, E. C. N. Richardson and Y. Fujita, “Casein Kinase 1 Is a Novel Negative Regulator of ECadherin-Based Cell-Cell Contacts,” Molecular and Cellular Biology, Vol. 27, No. 10, 2007, pp. 3804-3816.
doi:10.1128/MCB.01590-06
|
|
[88]
|
H. Aberle, A. Bauer, J. Stappert, A. Kispert and R. Kemler, “Beta-Catenin Is a Target for the Ubiquitin-Proteasome Pathway,” The EMBO Journal, Vol. 16, 1997, pp. 3797-3804. doi:10.1093/emboj/16.13.3797
|
|
[89]
|
B. C. Elias, T. Suzuki, A. Seth, F. Giorgianni, G. Kale, L. Shen, J. R. Turner, A. Naren, Dominic M. Desiderio and Radhakrishna Rao, “Phosphorylation of Tyr-398 and Tyr-402 in Occludin Prevents Its Interaction with ZO-1 and Destabi-Lizes Its Assembly at the Tight Junctions,” The Journal of Biological Chemistry, Vol. 284, 2009, pp. 1559-1569. doi:10.1074/jbc.M804783200
|
|
[90]
|
A. Kourtidis, S. P. Ngok and P. Z. Anastasiadis, “p120 Catenin: An Essential Regulator of Cadherin Stability, Adhe-Sion-Induced Signaling, and Cancer Progression,” Progress in Molecular Biology and Translational Science, Vol. 116, 2013, pp. 409-432.
doi:10.1016/B978-0-12-394311-8.00018-2
|
|
[91]
|
P. F. Song, H. S. Sekhon, Y. B. Jia, J. A. Keller, J. K. Blusztajn, G. P. Mark and E. R. Spindel, “Acetylcholine Is Synthesized by and Acts as an Autocrine Growth Factor for Small Cell Lung Carcinoma,” Cancer Research, Vol. 63, No. 1, 2003, pp. 214-221.
|
|
[92]
|
T. Schlereth., F. Birklein, K. an Haack, S. Schiffmann, H. Kilbinger, C. J. Kirkpatrick and I. Wessler, “In Vivo Release of Non-Neuronal Acetylcholine from the Human Skin as Measured by Dermal Microdialysis: Effect of Botulinum Toxin,” British Journal of Pharmacology, Vol. 147, No. 2, 2006, pp. 183-187.
doi:10.1038/sj.bjp.0706451
|
|
[93]
|
R. Y. Huang and G. G. Chen, “Cigarette Smoking, Cyclooxygenase-2 Pathway and Cancer,” Biochimica et Biophysica Acta, Vol. 1815, No. 2, 2011, pp. 158-169.
|
|
[94]
|
J. P. Raufman, R. Samimi, N. Shah, S. Khurana, J. Shant, C. Drachenberg, G. Xie, J. Wess and K. Cheng, “Genetic Ablation of M3 Muscarinic Receptors Attenuates Murine Colon Epithelial Cell Proliferation and Neoplasia,” Cancer Research, Vol. 68, No. 10, 2008, pp. 3573-3578.
doi:10.1158/0008-5472.CAN-07-6810
|
|
[95]
|
G. P. Boivin, K. Washington, K. Yang, J. M. Ward, T. P. Pretlow, R. Russell, D. G. Besselsen, V. L. Godfrey, T. Doetschman, W. F. Dove, H. C. Pitot, R. B. Halberg, S. H. Itzkowitz, J. Groden and R. J. Coffey, “Pathology of Mouse Models of Intestinal Cancer: Consensus Report and Recommendations,” Gastroenterology, Vol. 124, No. 3, 2003, pp. 762-77. doi:10.1053/gast.2003.50094
|
|
[96]
|
P. Song, H. S. Sekhon, A. Lu, J. Arredondo, D. Sauer, C. Gravett, G. P. Mark, S. A. Grando and E. R. Spindel, “M3 Muscarinic Receptor Antagonists Inhibit Small Cell Lung Carcinoma Growth and Mitogen-Activated Protein Kinase Phosphorylation Induced by Acetylcholine Secretion,” Cancer Research, Vol. 67, No. 8, 2007, pp. 3936-3944. doi:10.1158/0008-5472.CAN-06-2484
|
|
[97]
|
S. Zia, A. Ndoye, V. T. Nguyen and S. A. Grando, “Nicotine Enhances Expression of the Alpha 3, Alpha 4, Alpha 5, and Alpha 7 Nicotinic Receptors Modulating Calcium Metabolism and Regulating Adhesion and Motility of Respiratory Epithelial Cells,” Research Communications in Molecular Pathology and Pharmacology, Vol. 97, No. 3, 1997, pp. 243-262.
|
|
[98]
|
P. Dasgupta, W. Rizwani, S. Pillai, Kinkade R, Kovacs M, Rastogi S, Banerjee S, Carless M, Kim E, Coppola D, Haura E, Chellappan S., “Nicotine induces Cell Proliferation, Invasion and Epithelial-Mesenchymal Transition in a Variety of Human Cancer Cell Lines,” International Journal of Cancer, Vol. 124, No. 1, 2009, pp. 35-36.
doi:10.1002/ijc.23894
|
|
[99]
|
R. Davis, W. Rizwani, S. Banerjee, M. Kovacs, E. Haura, D. Coppola and S. Chellappan, “Nicotine Promotes Tumor Growth and Metastasis in Mouse Models of Lung Cancer,” PLoS One, Vol. 4, No. 10, 2009, Article ID: e7524. doi:10.1371/journal.pone.0007524
|
|
[100]
|
J. E. Michaelson, J. R. Ritzenthaler and J. Roman, “Regulation of Serum-Induced Fibronectin Expression by Protein Kinases, Cytoskeletal Integrity, and CREB,” American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 282, 2002, pp. L291-L301.
|
|
[101]
|
Y. Zheng, J. D. Ritzenthaler, J. Roman and S. W. Han, “Nicotine Stimulates Human Lung Cancer Cell Growth by Inducing Fibronectin Expression,” American Journal of Respiratory Cell and Molecular Biology, Vol. 37, No. 6, 2007, pp. 681-690. doi:10.1165/rcmb.2007-0051OC
|
|
[102]
|
P. L. Wei, L. J. Kuo, M. T. Huang, W. C. Ting, Y. S. Ho, W. Wang, J. An and Y. J. Chang, “Nicotine Enhances Colon Cancer Cell Migration by Induction of Fibronectin,” Annals of Surgical Oncology, Vol. 18, No. 6, 2011, pp. 1782-1790. doi:10.1245/s10434-010-1504-3
|
|
[103]
|
H. P. S. Wong, L. Yu, E. K. Y. Lam, E. K. K. Tai, W. K. K. Wu and C. H Cho, “Nicotine Promotes Colon Tumor Growth and Angiogenesis through Beta-Adrenergic Activation,” Toxicological Sciences, Vol. 97, No. 2, 2007, pp. 279-287. doi:10.1093/toxsci/kfm060
|
|
[104]
|
V. Y. Shin, W. K. K. Wu, Y. N. Ye, W. H. L. So, M. W. L. Koo, E. S. L. Liu, et al., “Nicotine Promotes Gastric Tumor Growth and Neovascularization by Activating Extracellular Signal-Regulated Kinase and Cyclooxygenase-2,” Carcinogenesis, Vol. 25, No. 12, 2004, pp. 2487-2495. doi:10.1093/ carcin/bgh266
|
|
[105]
|
V. Y. Shin, W. K. K. Wu, K. M. Chu, H. P. S. Wong, E. K. Y. Lam, E. K. K. Tai, et al., “Nicotine Induces Cyclooxygenase-2 and Vascular Endothelial Growth Factor Receptor-2 in Association with Tumor-Associated Invasion and Angiogenesis in Gastric Cancer,” Molecular Cancer Research, Vol. 3, 2005, pp. 607-615.
doi:10.1158/1541-7786.MCR-05-0106
|
|
[106]
|
R. D. Pullan, J. Rhodes, S. Ganesh, V. Mani, J. S. Morris, G. T. Williams, R. G. Newcombe, M. Russell, C. Feyerabend, G. Thomas, et al., “Transdermal Nicotine for Active Ulcerative Colitis,” The New England Journal of Medicine, Vol. 330, 1994, pp. 811-815.
doi:10.1056/NEJM199403243301202
|
|
[107]
|
J. Rhodes and G. Thomas, “Nicotine Treatment in Ulcerative Colitis,” Drugs, Vol. 49, No. 2, 1995, pp. 157-160. doi:10.2165/00003495-199549020-00001
|
|
[108]
|
J. R. Ingram, P. Routledge, J. Rhodes, R. W. Marshall, D. C. Buss, B. K. Evans, et al., “Nicotine Enemas for Treatment of Ulcerative Colitis: A Study of the Pharmacokinetics and Adverse Events Associated with Three Doses of Nicotine,” Alimentary Pharmacology & Therapeutics, Vol. 20, No. 8, 2004, pp. 859-865.
doi:10.1111/j.1365-2036.2004.02199.x
|
|
[109]
|
B. Tanja and B. Ulrich, “Inflammatory Bowel Disease and Smoking: A Review of Epidemiology, Pathophysiology, and Therapeutic Implications,” Inflammatory Bowel Diseases, Vol. 10, No. 6, 2004, pp. 848-859.
doi:10.1097/00054725-200411000-00019
|
|
[110]
|
W. J. Sandborn, “Severe Ulcerative Colitis,” Current Treatment Options in Gastroenterology, Vol. 2, No. 2, 1999, pp. 113-118. doi:10.1007/s11938-999-0038-x
|
|
[111]
|
J. E. Ghia, P. Blennerhassett, H. Kumar-Ondiveeran, E. F. Verdu and S. M. Collins, “The Vagus Nerve: A Tonic Inhibitory Influence Associated with Inflammatory Bowel Disease in a Murine Model,” Gastroenterology, Vol. 131, No. 4, 2006, pp. 1122-1130.
doi:10.1053/j.gastro.2006.08.016
|
|
[112]
|
S. A. Snoek, M. I. Verstege, E. P. van der Zanden, N. Deeks, D. C. Bulmer, M. Skynner, et al., “Selective Alpha7 Nicotinic Acetylcholine Receptor Agonists Worsen Disease in Experimental Colitis,” British Journal of Pharmacology, Vol. 160, No. 2, 2010, pp. 322-333.
doi:10.1111/j.1476-5381.2010.00699.x
|
|
[113]
|
A. P. Sykes, C. Brampton, S. Klee, C. L. Chander, C. Whelan and M. E. Parsons, “An Investigation into the Effect and Mechanisms of Action of Nicotine in Inflammatory Bowel Disease,” Inflammation Research, Vol. 49, No. 7, 2000, pp. 311-319. doi:10.1007/s000110050597
|
|
[114]
|
J. McGrath, J. W. Mcdonald and J. K. Macdonald, “Transdermal Nicotine for Induction of Remission in Ulcerative Colitis,” The Cochrane Database of Systematic Reviews, Vol. 18, No. 4, 2004, Article ID: CD004722.
|
|
[115]
|
V. E. McGilligan, J. M. W. Wallace, P. M. Heavey, D. L. Ridley and I. R. Rowland, “The Effect of Nicotine in Vitro on the Integrity of Tight Junctions in Caco-2 Cell Monolayers,” Food and Chemical Toxicology, Vol. 45, No. 9, 2007, pp. 1593-1598.
doi:10.1016/j.fct.2007.02.021
|
|
[116]
|
T. W. Costantini, M. Krzyzaniak, G. A. Cheadle, J. G. Putnam, A. M. Hageny, N. Lopez, et al., “Targeting α-7 Nicotinic Acetylcholine Receptor in the Enteric Nervous System: A Cholinergic Agonist Prevents Gut Barrier Failure after Severe Burn Injury,” The American Journal of Pathology, Vol. 181, No. 2, 2012, pp. 478-486.
doi:10.1016/j.ajpath.2012.04.005
|
|
[117]
|
T. W. Costantini, V. Bansal, M. Krzyzaniak, J. G. Putnam, C. Y. Peterson, W. H. Loomis, et al., “Vagal Nerve Stimulation Protects against Burn-Induced Intestinal Injury through Activation of Enteric Glia Cells,” American Journal of Physiology, Gastrointestinal and Liver Physiology, Vol. 299, No. 6, 2010, pp. G1308-G1318.
doi:10.1152/ajpgi.00156.2010
|
|
[118]
|
C. Bose, H. Zhang, K. B. Udupa and P. Chowdhury, “Activation of p-ERK1/2 by Nicotine in Pancreatic Tumor Cell Line AR42J: Effects on Proliferation and Secretion,” American Journal of Physiology, Gastrointestinal and Liver Physiology, Vol. 289, No. 5, 2005, pp. G926-G934.
doi:10.1152/ajpgi.00138.2005
|
|
[119]
|
H. Nakayama, S. Ueno, T. Ikeuchi and H. Hatanaka, “Regulation of Alpha3 Nicotinic Acetylcholine Receptor Subunit mRNA Levels by Nerve Growth Factor and Cyclic AMP in PC12 Cells,” Journal of Neurochemistry, Vol. 74, No. 4, 2000, pp. 1346-1354.
doi:10.1046/j.1471-4159.2000.0741346.x
|
|
[120]
|
T. Y. Ma, G. K. Iwamoto, N. T. Hoa, V. Akotia, A. Pedram, M. A. Boivin, et al., “TNF-Alpha-Induced Increase in Intestinal Epithelial Tight Junction Permeability Requires NF-Kappa B Activation,” American Journal of Physiology, Gastrointestinal and Liver Physiology, Vol. 286, No. 3, 2004, pp. G367-G376.
doi:10.1152/ajpgi.00173.2003
|
|
[121]
|
E. Hollenbach, M. Neumann, M. Vieth, A. Roessner, P. Malfertheiner and M. Naumann, “Inhibition of p38 MAP Kinaseand RICK/NF-kappab-Signaling Suppresses Inflammatory Bowel Disease,” FASEB Journal, Vol. 18, No. 13, 2004, pp. 1550-1552.
|
|
[122]
|
C. C. Hsu, J. C. Lien, C. W. Chang, C. H. Chang, S. C. Kuo and T. F. Huang, “Yuwen02f1 Suppresses LPS-Induced Endotoxemia and Adjuvant-Induced Arthritis Primarily through Blockade of ROS Formation, NFkB and MAPK Activation,” Biochemical Pharmacology, Vol. 85, No. 3, 2013, pp. 385-395.
doi:10.1016/j.bcp.2012.11.002
|
|
[123]
|
S. A. Benitah, P. F. Valerón and J. C. Lacal, “ROCK and Nuclear factor-KappaB-Dependent Activation of Cyclooxygenase-2 by Rho GTPases: Effects on Tumor Growth and Therapeutic Consequences,” Molecular Biology of the Cell, Vol. 14, No. 7, 2003, pp. 3041-3054.
doi:10.1091/mbc.E03-01-0016
|
|
[124]
|
A. I. Chernyavsky, J. Arredondo, T. Piser, E. Karlsson and S. A. Grando, “Differential Coupling of M1 Muscarinic and Alpha7 Nicotinic Receptors to Inhibition of Pemphigus Acantholysis,” The Journal of Biological Chemistry, Vol. 283, 2008, pp. 3401-3408.
doi:10.1074/jbc.M704956200
|
|
[125]
|
M. L. van Hoek, C. S. Allen and S. J. Parsons, “Phosphotyrosine Phosphatase Activity Associated with c-Src in Large Multimeric Complexes Isolated from Adrenal Medullary Chromaffin Cells,” The Biochemical Journal, Vol. 326, Pt. 1, 1997, pp. 271-277.
|
|
[126]
|
J. Joseph, B. Niggemann, K. S. Zaenker and F. Entschladen, “The Neurotransmitter Gamma-Aminobutyric Acid Is an Inhibitory Regulator for the Migration of SW 480 Colon Carcinoma Cells,” Cancer Research, Vol. 62, No. 22, 2002, pp. 6467-6469.
|
|
[127]
|
H. M. Schuller, H. A. N. Al-Wadei and M. Majidi, “GABAB Receptor Is a Novel Drug Target for Pancreatic Cancer,” Cancer, Vol. 112, No. 4, 2008, pp. 767-778.
doi:10.1002/cncr.23231
|
|
[128]
|
H. Kawai and D. K. Berg, “Nicotinic Acetylcholine Receptors Containing Alpha 7 Subunits on Rat Cortical Neurons Do Not Undergo Long-Lasting Inactivation Even When Up-Regulated by Chronic Nicotine Exposure,” Journal of Neurochemistry, Vol. 78, No. 6, 2001, pp. 1367-1378. doi:10.1046/j.1471-4159.2001.00526.x
|
|
[129]
|
P. Ambrosi and A. Becchetti, “Targeting Neuronal Nicotinic Receptors in Cancer: New Ligands and Potential Side-Effects,” Recent Patents on Anti-Cancer Drug Discovery, Vol. 8, No. 1, 2013, pp. 38-52.
|