Management of the Case of a Young Female Patient with Multiple Malignancies and Germline R24P CDKN2A Gene Mutation


The case of a young female patient with metachronous primary melanomas, advanced breast and pancreatic cancers is reported. The 5 different tumors diagnosed within six years, were managed with curative intent. Genetic analysis revealed the mutation of the R24P CDKN2A gene in a heterozygote form in both the patient and her father. Careful tertiary prevention during the follow-up of the patient is needed.

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G. Uhercsák, Á. Dobi, R. Gyulai, J. Oláh, L. Kaizer, K. Ormándi, A. Cserháti, G. Lázár, G. Farkas and Z. Kahán, "Management of the Case of a Young Female Patient with Multiple Malignancies and Germline R24P CDKN2A Gene Mutation," Journal of Cancer Therapy, Vol. 4 No. 7A, 2013, pp. 18-20. doi: 10.4236/jct.2013.47A004.

Conflicts of Interest

The authors declare no conflicts of interest.


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