Metastatic peritoneal sarcomatosis from radiation-induced osteosarcoma in a patient with previously treated pelvic Ewing’s sarcoma: Report of a case

Rajendra Kumar, Romil Y. Patel, John E. Madewell, Tariq J. Al-Zaid, Jeanne M. Meis

Department of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, USA.
Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, USA.

DOI: 10.4236/ojcd.2013.32010                

Abstract

Metastatic peritoneal sarcomatosis most commonly occurs from primary soft tissue sarcomas arising either within the abdomen or extremities. Metastatic peritoneal sarcomatosis from an osteosarcoma is extremely rare; only six cases have previously been reported. We report the first case of metastatic peritoneal sarcomatosis originating from radiation-induced osteoblastic osteosarcoma in a 22-year-old woman who had previously been treated for pelvic Ewing’s sarcoma. Abdominal computed tomography, bone scintigraphy and FDG PET/CT demonstrated extensive finely nodular disseminated peritoneal lesions. Histopathologic examination of these peritoneal lesions revealed osteosarcomatosis. In summary, we describe an unusual case of metastatic peritoneal sar comatosis from secondary osteosarcoma arising in a previously irradiated pelvicEwing’s sarcoma.

Keywords

Peritoneal Sarcomatosis; Peritoneal Osteosarcomatosis; Radiation-Induced Osteosarcoma; Radiation-Induced Bone Sarcoma

Conflicts of Interest

The authors declare no conflicts of interest.

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