Pyoderma gangrenosum affecting the mouth


Pyoderma gangrenosum is a rare ulcerative cutaneous disorder commonly associated with systemic diseases such as inflammatory bowel diseases. This paper reports a case of pyoderma gangrenosum affecting the mouth and the skin associated with ulcerative colitis. A Medline search in English literature from 1961 to 2012 revealed only 11 documented cases of pyoderma gangrenosum with oral involvement. Previous reported cases of oral cavity involvement have shown that the most common sites of manifestation are the tongue, palate, and tonsillar fauces. This case emphasizes the importance of including inflammatory bowel diseases and their manifestations in the differential diagnosis of ulcerative lesions in the oral cavity.

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Curi, M. , Cardoso, C. , Koga, D. , Zardetto, C. and Araújo, S. (2013) Pyoderma gangrenosum affecting the mouth. Open Journal of Stomatology, 3, 142-145. doi: 10.4236/ojst.2013.32026.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Yco, M.S., Warnock, G.R., Cruickshank, J.C. and Burnnet, J.R. (1988) Pyoderma gangrenosum involving the head and neck. Laryngoscope, 98, 765-768. doi:10.1288/00005537-198807000-00016
[2] Setterfield, J.F., Shirlaw, P.J., Challacombe, S.J. and Black, M.M. (2001) Pyoderma gangrenosum associated with severe oropharyngeal involvement and IgA paraproteinaemia. British Journal of Dermatology, 144, 393-396. doi:10.1046/j.1365-2133.2001.04035.x
[3] Callen, J.P. (1998) Pyoderma gangrenosum. Lancet, 351, 581-585. doi:10.1016/S0140-6736(97)10187-8
[4] Paramkusam, G., Meduri, V. and Gangeshetty, N. (2010) Pyoderma gangrenosum with oral involvement—Case report and review of the literature. International Journal of Oral Science, 2, 111-116. doi:10.4248/IJOS10032
[5] Basu, M. and Asquith, P. (1980) Oral manifestations of inflammatory bowel disease. Journal of Clinical Gastroenterology, 9, 307-321.
[6] Margoles, J.S. and Wenger, J. (1961) Stomal ulceration associated with pyoderma gangrenosum and ulcerative colitis. Report of two cases. Gastroenterology, 41, 594- 598.
[7] Kennedy, K.S., Prendergast, M.L. and Sooy, C.D. (1987) Pyoderma gangrenosum of the oral cavity, nose and larynx. Otolaryngology—Head and Neck Surgery, 97, 487- 490.
[8] Snyder, R.A. (1986) Pyoderma gangrenosum involving the head and neck. Archives of Dermatology, 122, 295- 302. doi:10.1001/archderm.1986.01660150073019
[9] Hiromi, T. (2008) Case of pyoderma gangrenosum showing oral and genital ulcers, misdiagnosed as Behcet’s disease at first medical examination. The Journal of Dermatology, 35, 289-292. doi:10.1111/j.1346-8138.2008.00468.x
[10] Yusuf, H. and Ead, R.D. (1985) Pyoderma gangrenosum with involvement of the tongue. British Journal of Oral and Maxillofacial Surgery, 23, 241-250. doi:10.1016/0266-4356(85)90040-3
[11] Burnsting, L.A., Goeckrman, W.H. and O’Leary, P.A. (1930) Pyoderma (ecthyma) gangrenosum: Clinical and experimental observations in five cases occurring in adults. Archives of Dermatology, 22, 655-690. doi:10.1001/archderm.1930.01440160053009
[12] Fatahzadeh, M. (2009) Inflammatory bowel disease. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 108, 1-10. doi:10.1016/j.tripleo.2009.07.035
[13] Ruiz-Roca, J.A., Berini-Aytés, L. and Gay-Escoda, C. (2005) Pyostomatitis vegetans. Report of two cases and review of the literature. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 99, 447-454. doi:10.1016/j.tripleo.2003.08.022
[14] Mani, V. (2002) Pyoderma gangrenosum. The International Journal of Lower Extremity Wounds, 1, 43. doi:10.1177/153473460200100106

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