Nuclear-Chemical Synthesis of 1,4-Diazine Quaternary Salts


Ion-molecular reactions of nucleogenic phenyl cations with the nucleophilic centers of 1,4-diazines have been investigated for the first time. Previously unknown tritium labeled N-phenyl quaternary derivatives of pyrazine and quinoxaline, which are potential radioactive biomarkers, have been obtained by nuclear-chemical method.

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N. Shchepina, V. Avrorin and G. Badun, "Nuclear-Chemical Synthesis of 1,4-Diazine Quaternary Salts," Open Journal of Synthesis Theory and Applications, Vol. 2 No. 2, 2013, pp. 51-55. doi: 10.4236/ojsta.2013.22006.

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The authors declare no conflicts of interest.


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