Failed Completion Pneumonectomy for Early Recurrent Pleomorphic Carcinoma: A Case Report

Abstract

We report a patient with a large pulmonary pleomorphic carcinoma (PPC) in the left upper lobe greater than 10 cm in diameter. She underwent left upper lobectomy with mediastinal lymph node dissection and concomitant resection of the left phrenic nerve, vagus nerve and pericardium. She received adjuvant chemotherapy, but had tumor recurrence. We then performed left completion pneumonectomy, but could not remove the tumor completely because of rapid tumor invasion to the left atrium. Urgent surgery should be considered for recurrent resectable PPC.

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M. Uehara, A. Watanabe, J. Nakazawa, R. Harada, M. Miyajima, S. Nakashima, T. Obama and T. Higami, "Failed Completion Pneumonectomy for Early Recurrent Pleomorphic Carcinoma: A Case Report," Open Journal of Thoracic Surgery, Vol. 3 No. 1, 2013, pp. 1-3. doi: 10.4236/ojts.2013.31001.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] E. Brambilla, W. D. Travis, T. V. Colby, B. Corrin and Y. Shimosato, “The New World Health Organization Classification of Lung Tumors,” European Respiratory Journal, Vol. 18, No. 6, 2001, pp. 1059-1068. doi:10.1183/09031936.01.00275301
[2] M. Uehara, A. Watanabe, T. Nakajima, S. Nakashima, T. Higami and N. Inoue, “Pulmonary Pleomorphic Carcinoma; an Investigation of Thirteen Cases,” Kyobu Geka, Vol. 62, No. 2, 2009, pp. 89-93.
[3] T. Yuki, T. Sakuma, C. Ohbayashi, M. Yohimura, N. Tsubota, Y. Okita, et al., “Pleomorphic Carcinoma of the Lung: A Surgical Outcome,” The Journal of Thoracic and Cardiovascular Surgery, Vol. 134, No. 2, 2007, pp. 399-404. doi:10.1016/j.jtcvs.2007.04.018
[4] N. F. Fishback, W. D. Travis, C. A. Moran, D. G. Guinee Jr., W. F. McCarthy and M. N. Koss, “Pleomorphic (Spindle/Giant Cell) Carcinoma of the Lung. A Clinicopathologic Correlation of 78 Cases,” Cancer, Vol. 73, No. 12, 1994, pp. 2936-2945. doi:10.1002/1097-0142(19940615)73:12<2936::AID-CNCR2820731210>3.0.CO;2-U
[5] J. Y. Hong, M. K. Choi, J. E. Uhm, M. J. Park, J. Lee, Y. H. Park, et al., “The Role of Palliative Chemotherapy for Advanced Pulmonary Pleomorphic Carcinoma,” Medical Oncology, Vol. 26, No. 3, 2009, pp. 287-291. doi:10.1007/s12032-008-9117-4
[6] K. W. Lee, Y. J. Kim, J. H. Kim, S. M. Bang, J. H. Chung and J. S. Lee, “Two Consecutive Cases of Platinum-Refractory Pulmonary Pleomorphic Carcinoma that Showed Dramatic Responses to MAID (Mensa, Doxorubicin, Ifosfamide and Dacarbazine) Chemotherapy,” Japanese Journal of Clinical Oncology, Vol. 41, No. 3, 2011, pp. 430-433. doi:10.1093/jjco/hyq180

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