Thromboelastography Use in the Perioperative Transfusion Management of a Patient with Hemophilia A Undergoing Liver Transplantation ()
Alejandro Mejia,
Maria L. Mendoza,
Catalina Mejia,
Gong W. Lee
Methodist Dallas Medical Center, Dallas, USA.
Transplant Surgery, The Liver Institute at Methodist Dallas, Dallas, USA.
DOI: 10.4236/ojots.2013.31003
PDF
HTML XML
5,506
Downloads
8,583
Views
Citations
Abstract
The thrombelastogram is a method used to monitor clotting dynamics. Thrombelastography (TE) has been used to guide therapy of coagulation disorders mostly in cardiac surgery but also in liver surgery. TE is a useful tool for perioperative management of patients at risk for coagulopathy. There are several reports describing the use of the thrombelastogram in patients undergoing orthotopic liver transplantation (OLT), but only few cases include patients with both liver disease and inherited bleeding disorders. We describe the use of TE in a patient with hemophilia A and advanced cirrhosis undergoing OLT.
Share and Cite:
Mejia, A. , Mendoza, M. , Mejia, C. and Lee, G. (2013) Thromboelastography Use in the Perioperative Transfusion Management of a Patient with Hemophilia A Undergoing Liver Transplantation.
Open Journal of Organ Transplant Surgery,
3, 13-17. doi:
10.4236/ojots.2013.31003.
Conflicts of Interest
The authors declare no conflicts of interest.
References
[1]
|
E. G. Pivalizza, “Perioperative Use of Thrombelastograph® in Patients with Inherited Bleeding Disorders,” Journal of Clinical Anesthesia, Vol. 15, No. 5, 2003, pp. 366-370. doi:10.1016/S0952-8180(03)00022-9
|
[2]
|
M. Franchini, N. Nicolini and F. Capra, “Treatment of Hepatitis C in Hemophiliacs,” American Journal of Hematology, Vol. 81, No. 9, 2006, pp. 696-702.
doi:10.1002/ajh.20701
|
[3]
|
J. Wilde, P. Teixeira, S. R. Bramhall, B. Gunson, D. Mutimer and D. F. Mirza, “Liver Transplantation in Haemophilia,” British Journal of Haematology, Vol. 117, No. 4, 2002, pp. 952-956.
doi:10.1046/j.1365-2141.2002.03528.x
|
[4]
|
M. Coakley, K. Reddy, I. Mackie and S. Mallet, “Transfusion Triggers in Orthotopic Liver Transplantation: A Comparison of Thromboelastometry Analyzer, the Thromboelastogram, and Conventional Coagulation Tests,” Journal of Cardiothoracic and Vascular Anesthesia, Vol. 20, No. 4, 2006, pp. 548-553.
doi:10.1053/j.jvca.2006.01.016
|
[5]
|
A. A. Ashrani, M. T. Reding, A. Shet, J. Osip, A. Humar, J. R. Lake, et al., “Successful Liver Transplantation in a Patient with Severe Haemophilia A and a High-Titer Factor VIII Inhibitor,” Haemophilia, Vol. 10, No. 6, 2004, pp. 735-737.
|