Myxoid Meningioma: An Example of a Rare Brain Tumour of Difficult Diagnosis

Javier Ortiz, María Dolores Ludeña, Jesús Gonçalves, Sofía Del Carmen, Ángel Maillo, Agustín Bullon

Neuro- surgery Department, Hospital Virgen de la Vega, (Complejo Hospitalario de Salamanca), Salamanca, Spain.
Pathology Department, Hospital Universitario de Salamanca, (Complejo Hospitalario de Salamanca), Salamanca, Spain.

DOI: 10.4236/ojpathology.2013.31009                

Abstract

We present a case of a Myxoid Meningioma noticed in a 43-year-old woman. The patient, who had no noteworthy medical antecedents, showed repeated focal epileptic crisis. Imaging studies (MR and CT) showed a solitary and well delimited tumour located in the frontral lobe. Once extirpated, the histological study revealed a neoplasm of myxoid and benign appearance, with elongated and uniform cells, with no atypias and a very low mitotic index. Immunohistochemisty studies (positivity for Vimentin and Epithelial Membrane Antigen, and negativity for the other markers) as well as physical and radiological examination of the patient (absence of tumours in any other location), suggested the diagnosis of a Myxoid Meningioma, which was confirmed by electron microscopy (by the presence of desmosomes). We also revise the characteristics of Myxoid Meningiomas, an absolutely exceptional primary tumour of the central nervous system.

Keywords

Myxoid Meningioma; Immunohistochemistry; Electron Microscopy

Conflicts of Interest

The authors declare no conflicts of interest.

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