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Tubulointerstitial Nephritis Complicated with Primary Sjögren’s Syndrome under Treatment for Type 2 Diabetes Mellitus

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DOI: 10.4236/ojneph.2012.24017    3,157 Downloads   5,440 Views  

ABSTRACT

Tubulointerstitial nephritis complicated by primary Sj?gren’s syndrome in a patient under treatment for type 2 diabetes mellitus was diagnosed in the early stage of the disease by renal biopsy. The symptoms of primary Sj?gren’s syndrome, such as thirst and polydipsia, were masked by the characteristic symptoms of type 2 diabetes mellitus. An association between sicca symptoms and diabetes mellitus (types 1 and 2) has been previously reported. Hence, it is possible that there are common underlying immunological mechanisms between primary Sj?gren’s syndrome and diabetes mellitus of both types. Intervention with steroids in a timely manner appears to have prevented or slowed the progression of re- nal impairment.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

S. Antoku, H. Ito, M. Mifune, H. Nawata and M. Kato, "Tubulointerstitial Nephritis Complicated with Primary Sjögren’s Syndrome under Treatment for Type 2 Diabetes Mellitus," Open Journal of Nephrology, Vol. 2 No. 4, 2012, pp. 105-108. doi: 10.4236/ojneph.2012.24017.

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