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Splenic Infarction Associated with Acute Brucellosis: A Case Report

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DOI: 10.4236/aid.2012.24014    3,596 Downloads   6,529 Views   Citations

ABSTRACT

We report a case of a 21-year-old shepherd who presented with fever, left hypochondrium pain and splenomegaly. Blood tests showed thrombocytopenia and high liver enzymes. Computed tomography scan revealed the presence of hypodense lesions suggestive of splenic infarction. Echocardiography was without abnormalities. Laboratory evaluation for thrombophilia was negative. A bone marrow aspiration and a bone marrow biopsy were normal. Brucella serology was positive. The patient was treated with doxycycline, rifampicin and streptomycin for 12 weeks. Fever, abdominal pain and thrombocytopenia resolved promptly. At one year of follow-up, he remained well and no splenic infarction could be detected on ultrasonography.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

W. Hachfi, F. Bellazreg, A. Atig, N. Ben Lasfar, N. Kaabia and A. Letaief, "Splenic Infarction Associated with Acute Brucellosis: A Case Report," Advances in Infectious Diseases, Vol. 2 No. 4, 2012, pp. 89-91. doi: 10.4236/aid.2012.24014.

References

[1] A. Sevinc, N. Buyukberber, C. Camci, S. Buyukberber and T. Karsligil, “Thrombocytopenia in Brucellosis: Case Report and Literature Review,” Journal of the National Medical Association, Vol. 97, No. 2, 2005, pp. 290-293.
[2] M. Odeh, N. Pick and A. Oliven, “Deep Venous Thrombosis Associated with Acute Brucellosis: A Case Report,” Angiology, Vol. 51, No. 3, 2000, pp. 253-256. doi:10.1177/000331970005100310
[3] J. Sanchez-Gonzalez, T. Garcia-Delange, F. Martos and J. D. Colmenero, “Thrombosis of the Abdominal Aorta Secondary to Brucella Spondylitis,” Infection, Vol. 24, No. 3, 1996, pp. 261-262. doi:10.1007/BF01781108
[4] M. Capell, T. Simon and M. Tiku, “Splenic Infarction Associated with Anticardiolipin Antibodies in a Patient with Acquired Immunodeficiency Syndrome,” Digestive Disease and Sciences, Vol. 38, No. 6, 1993, pp. 1152-1155. doi:10.1007/BF01295735
[5] C. M. Witmer, A. P. Steenhoff, S. S. Shah and L. J. Raffini, “Mycoplasma Pneumoniae, Splenic Infarct, and Transient Antiphospholipid Antibodies: A New Association,” Pediatrics, Vol. 119, No. 1, 2007, pp. 292-295.
[6] F. Salgado, M. Grana, V. Ferrer, A. Lara and T. Fuentes, “Splenic Infarction Associated with Acute Brucella Melitensis Infection,” European Journal of Clinical Microbiology & Infectious Diseases, Vol. 21, No. 1, 2002, pp. 63-64. doi:10.1007/s10096-001-0655-3
[7] C. Ruggeri, V. Tulino, T. Foti, L. Carcione, D. Vita, C. Visalli, et al., “Brucellosis and Splenic Infarction: A Case in Pediatric Age,” Minerva Pediatrica, Vol. 53, No. 6, 2001, pp. 577-579.
[8] M. Antopolsky, N. Hiller, S. Salameh, B. Goldshtein and R. Stalnikowicz, “Splenic Infarction: 10 Years of Experience,” American Journal of Emergency Medicine, Vol. 27, No. 3, 2009, pp. 262-265. doi:10.1016/j.ajem.2008.02.014
[9] I. Dilek, A. Durmus, M. K. Karahocagil, H. Akdeniz, H. Karsen, A. I. Baran, et al., “Hematological Complications in 787 Cases of Acute Brucellosis in Eastern Turkey,” Turkish Journal of Medical Sciences, Vol. 38, No. 5, 2008, pp. 421-424.
[10] M. Ozen, ü. Ozgen and S. Güngor, “Management of Brucella-Induced Thrombocytopenic Purpura,” The Pediatric Infectious Disease Journal, Vol. 3, No. 3, 2009, pp. 83-85.

  
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