Lactic Acidosis and Atrial Tachycardia: Unusual Presentations of Disseminated Burkitt-Like Lymphoma
Hazem El-Osta, Abdulrahman Abdulbaki, Prakash Peddi, Amol Takalkar, James Cotelingam, Diana Veillon, Andres Vargas, Nuri Akkus, Gerhard C. Hildebrandt
Department of Medicine, Division of Cardiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Department of Medicine, Division of Hematology oncology, Louisiana State University Health Sciences Center, Shreveport, USA.
Department of Medicine, Division of internal medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Department of Nuclear Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Department of Pathology, Louisiana State University Health Sciences Center, Shreveport, USA.
DOI: 10.4236/jct.2012.35075   PDF    HTML     4,679 Downloads   7,418 Views  


Lactic acidosis is a rare complication of malignancies and is seen more frequently in high grade lymphoma and leukemia. Although, its pathogenesis is not well understood, it remains a surrogate of poor prognosis. Herein, we present a case of Burkitt-like lymphoma presenting with metabolic abnormalities including lactic acidosis and hypoglycemia along with atrial tachycardia. We will discuss the different mechanisms involved in these metabolic disturbances and we will provide insight on novel therapeutic strategies based on our understanding of the underlying pathophysiology.

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H. El-Osta, A. Abdulbaki, P. Peddi, A. Takalkar, J. Cotelingam, D. Veillon, A. Vargas, N. Akkus and G. C. Hildebrandt, "Lactic Acidosis and Atrial Tachycardia: Unusual Presentations of Disseminated Burkitt-Like Lymphoma," Journal of Cancer Therapy, Vol. 3 No. 5, 2012, pp. 589-594. doi: 10.4236/jct.2012.35075.

Conflicts of Interest

The authors declare no conflicts of interest.


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