Selenium Content in Blood of Donors from the North of Rio de Janeiro State, Brazil


Selenium is an element which participates in antioxidant enzymes. A medium and long term lack of such element is associated, mainly, with heart disease, joint and bone structure problems and thyroid activity. Selenium contents in blood reflect its ingestion and food content variation. It depends on soil characteristics, such as pH and selenium presence. There are few studies concerning selenium levels in food and blood in Brazil. Therefore, the objective of this research was to determine selenium content in a blood donor group in Rio de Janeiro state, conducted from December 2008 to March 2009. From the donated blood to Regional Blood Center of Campos dos Goytacazes, 4.0 mL were submitted to selenium analysis through atomic absorption spectrometry of hydride generation and organic matter oxidation wet basis with nitric and perchloric acid. Selenium content varied from 75 ± 16 ng·g-1 for females and 70 ± 21 ng·g-1 for males. There was no significant difference among selenium contents in blood from donors of different gender, age and residence. Seventy four percent of donors had selenium content in blood below 70 ng·mL-1, the lowest level for maximum selenoproteins production, according to the Nutritional Prevention Cancer.

Share and Cite:

J. Silva, K. Ferreira, S. Almeida and L. Duarte, "Selenium Content in Blood of Donors from the North of Rio de Janeiro State, Brazil," Food and Nutrition Sciences, Vol. 3 No. 9, 2012, pp. 1197-1201. doi: 10.4236/fns.2012.39157.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] C. S. Broome, F. McArdle, F. Andrews, et al., “An Increase in Selenium Intake Improves Immune Function and poliovirus Handling in Adults with Marginal Selenium Status,” American Journal of Clinical Nutrition, Vol. 80, 2004, pp. 154-162.
[2] M. B. Mihailovi?, D. M. Avramovi?, I. B. Jovanovi?, et al., “Blood and Plasma Selenium Levels and GSH-Px Activities in Patients with Arterial Hypertension and Chronic Heart Disease,” Journal of Environmental Pathology, Toxicology and Oncology, Vol. 17, 1998, pp. 285-289.
[3] J. R. Arthur, G. Bermano, J. H. Mitchell, et al., “Regulation of Selenoprotein Gene Expression and Thyroid Hormone Metabolism,” Biochemical Society Transactions, Vol. 24, 1996, pp. 384-388.
[4] O. Augusto, “Radicais Livres: Bons, Maus e Naturais,” Oficina do Texto, S?o Paulo, 2006.
[5] G. C. Ghisleni, “Altera??es Comportamentais e Neuroquímicas Causadas Por Compostos Organicos de Selênio,” Ph.D. Dissertation, Santa Maria Biological Sciences UFSM, Santa Maria, 2007.
[6] R. V. Cauwenbergh, H. Robberechta, V. V. Vlaslaerb, et al., “Plasma Selenium Levels in Healthy Blood Bank Donors in the Central-Eastern Part of Belgium,” Journal of Trace Elements in Medicine and Biology, Vol. 21, 2007, pp. 225-233. doi:10.1016/j.jtemb.2007.06.003
[7] World Health Organization/Food and Agriculture Organization of the United Nations, “Human Vitamin and Mineral Requirements,” Food and Nutrition Division, FAO Rome, 2001.
[8] K. E. Hill, Y. Xia, B. Akesson, et al., “Selenoprotein P Concentration in Plasma is An Index of Selenium Status in Selenium-Deficient and Selenium-Supplemented Chinese Subjects,” Journal of Nutrition, Vol. 126, 1996, pp. 138-145.
[9] A. J. Duffield, C. D. Thomson, K. E. Hill, et al., “An Estimation of Selenium Requirements for New Zealanders,” American Journal of Clinical Nutrition, Vol. 70, 1999, pp. 896-903.
[10] A. L. Duffield-Lillico, M. E. Reid, B. W. Turnbull, et al., “Baseline Characteristics and the Effect of Selenium Supplementation on Cancer Incidence in a Randomized Clinical Trial: A Summary Report of the Nutritional Prevention of Cancer Trial,” Cancer Epidemiology Biomaarkers & Prevention, Vol. 11, 2002, pp. 630-639.
[11] K. S. Ferreira, J. C. Gomes, C. R. Bellato, et al., “Concentra??es de Selênio em Alimentos Consumidos no Brasil,” Pan American Journal of Public Health, Vol. 11, 2002, pp. 172-177.
[12] N. A. Clack, K. Teschke, K. Rideout, et al., “Trace Elements Levels in Adults from the West Coast of Canadá and Associations with Age, Gendre, Diet, Activities and Levels of Other Trace Elements,” Chemosphere, Vol. 70, No. 1, 2007, pp. 155-164. doi:10.1016/j.chemosphere.2007.06.038
[13] C. D. Thomson, M. F. Robinson, J. A. Butler, et al., “Long-Term Supple-Mentation with Selenate and Selenomethionine: Selenium and Gluta-Thione Peroxidase,” (EC in Blood Components of New Zealand Women,” British Journal of Nutrition, Vol. 69, No. 2, 1993, pp. 577-588. doi:10.1079/BJN19930057
[14] E. N. Allen, P. N. Appleby, A. W. Roddam, et al., “Plasma Selenium Concentration and Prostate Cancer Risk: Results from the European Prospective Investigation into Cancer and Nutrition,” American Journal of Clinical Nutrition, Vol. 88, 2008, pp. 1567-1575. ”doi:10.3945/ajcn.2008.26205
[15] J. Burri, M. Haldimann and V. Dudler, “Selenium Status of the Swiss Population: Assessment and Change over a Decade,” Journal of Trace Elements in Medicine and Biology, Vol. 22, No. 2, 2008, pp. 112-119. doi:10.1016/j.jtemb.2007.11.002
[16] M. S. Saiki, M. Nairo, O. Jahul, et al., “Níveis de Selênio e Zinco Numa Popula??o de Idosos Saudáveis de um Hospital Universitário,” Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol. 45, 2009, p. 118.
[17] M. Lemire, D. Mergler, M. Fillion, et al., “Elevated Blood Selenium Levels in the Brazilian Amazon,” Science of the Total Environment, Vol. 366, 2006, pp. 101111. doi:10.1016/j.scitotenv.2005.08.057
[18] M. Navarro-Alarcon, “M & C Cabrera-Vique Selenium in Food and the Human Body: A Review,” Science of the Total Environment, Vol. 400, No. 1-3, 2008, pp. 115-141. doi:10.1016/j.scitotenv.2008.06.024
[19] M. A. Moore, R. C. Wander, Y. M. Xia, et al., “Selenium Supplementation of Chinese Women with Habitually Low Selenium Intake Increases Plasma Selenium, Plasma Glutathione Peroxidase Activity and Milk Selenium, but not Milk Glutathione Peroxidase Activity,” Journal of Nutritional Biochemistry, Vol. 11, No. 6, 2000, pp. 341-347. doi:10.1016/S0955-2863(00)00089-9
[20] J. Nève, “Human Selenium Supplementation as Assessed by Changes in Blood Selenium Concentration and Glutathione Peroxidase Activity,” Journal of Trace Elements in Medicine and Biology, Vol. 9, No. 2, 1995, pp. 65-73. doi:10.1016/S0946-672X(11)80013-1

Copyright © 2023 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.