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Feasibility of Performing Sentinel Lymph Node Biopsy (SLNB) after Mastectomy: A Case Report

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DOI: 10.4236/jct.2010.12015    3,702 Downloads   7,194 Views   Citations


Introduction: Previous mastectomy remains a contraindication to SLNB as normal drainage patterns of the breast can be disturbed. Patients diagnosed with DCIS on core biopsy and later found to have microinvasive or invasive carci-noma at the time of mastectomy are deprived of the opportunity for SLNB and need to undergo axillary dissection. We explored the option and feasibility of performing SLNB in a 39-year-old female who underwent a simple mastectomy without axillary sampling for extensive DCIS and later found to have microinvasive ductal carcinoma on permanent pathology. Results: Lymphatic mapping using subdermal injection of 99mTc-labeled sulfur colloid and blue dye led to the identification of five SLNs. Histopathologic examination showed no metastasis. Conclusion: SNLB is feasible in this setting. However, before its use is routinely adopted, its feasibility and accuracy has to be demonstrated in larger num-bers of patients in whom a negative SLNB is followed by a completion axillary dissection.

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The authors declare no conflicts of interest.

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H. Bu-Ali and E. Mamouna, "Feasibility of Performing Sentinel Lymph Node Biopsy (SLNB) after Mastectomy: A Case Report," Journal of Cancer Therapy, Vol. 1 No. 2, 2010, pp. 91-93. doi: 10.4236/jct.2010.12015.


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