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Primary Chondrosarcoma of the Mammary Gland of a Spayed American Akita Bitch: A Case Report

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DOI: 10.4236/ojvm.2012.22014    3,394 Downloads   6,226 Views   Citations

ABSTRACT

An eleven-year-old spayed American Akita bitch rapidly developed a mammary tumour which was surgically removed. The histological examination revealed the tumour to be a sarcoma that presented positive immunohistochemical staining against vimentin and protein S 100. There was no staining against pan-actin. Based on the histological aspect and the pattern of immunohistochemical staining the diagnosis of primary extraskeletal chondrosarcoma of the mammary gland was considered most probable. Two months later the patient was euthanized with recurrent local tumour and metastases in the lungs.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

F. Comhaire, I. Matteeusen and H. Cock, "Primary Chondrosarcoma of the Mammary Gland of a Spayed American Akita Bitch: A Case Report," Open Journal of Veterinary Medicine, Vol. 2 No. 2, 2012, pp. 81-83. doi: 10.4236/ojvm.2012.22014.

References

[1] B. B. Koch, L. H. Karnell, H. T. Hoffman, L. W. Apostolakis, R. A. Robinson, W. Zhen and H. R. Menck, “National Cancer Database Report on Chondrosarcoma of the Head and Neck,” Head Neck, Vol. 22, No. 4, 2000, pp. 408-425. doi:10.1002/1097-0347(200007)22:4<408::AID-HED15>3.0.CO;2-H
[2] D. Meuten, “Tumors in Domestic Animals,” Iowa State Press, Iowa, 2002, p. 788. doi:10.1002/9780470376928
[3] M. W. Woldemeskel and C. D. Grice, “Pathology in Practice. Extraskeletal Chondroblastic Osteosarcoma,” Journal of the American Veterinary Medicine Association, Vol. 238, No. 3, 2011, pp. 297-299. doi:10.2460/javma.238.3.297
[4] G. Serin and A. Aydogan, “Chondrosarcoma in the Mammary Gland of a Bitch: A Case Report,” Veterinari Medicina, Vol. 54, 2009, pp. 543-546.
[5] J. F. Hampe and W. Misdorp, “Tumors and Dysplasias of the Mammary Gland,” Bulletin of the World Health Organization, Vol. 50, 1974, p. 114.
[6] S. E. Lana, G. R. Rutteman, E. G. Macewen and S. J. Withrow, “Tumors of the Mammary Gland, 357,” In: S. J. Withdrow and E. G. Macewen, Eds., Small Animal Clinical Oncology, W.B. Saunders, Philadelphia, 2001, p. 864.
[7] A. K. Patnaik, “Canine Extraskeletal Osteosarcoma and Chondrosarcoma. A Clinicopathologic Study of 14 Cases,” Veterinary Pathology, Vol. 27, No. 1, 1990, pp. 46-55. doi:10.1177/030098589002700107
[8] C. A. Popovitch, M. J. Weinstein, M. H. Goldschhmidt and F. S. Shofer, “Chondrosarcoma: A Retrospective Study of 97 Dogs (1987-1990),” Journal of the American Animal Hospital Association, Vol. 30, 1994, pp. 81-85.
[9] F. Martins, E. Tamaso and J. L. Guerra, “Retrospective Review and Systematic Study of Mammary Tumors in Dogs and Charateristics of the Extracellular Matrix,” Brazilian Journal of Research Animal Science, Vol. 39, No. 1, 2002, pp. 38-42.
[10] B. R. Lee, S. H. Lee, H. Lee, H. Kim, D. Y. Kim and J. Choi, “Abdominal Aortic Chondrosarcoma in a Dog,” Journal of Veterinary Medical Science, Vol. 73, No. 11, 2011, pp. 1473-1476. doi:10.1292/jvms.10-0544
[11] S. Chikata, S. Nakamura, R. Katayama, S. Yanagisawa, Y. Matsuo, I. Yamane and K. Takahashi, “Primary Chondrosarcoma in the Liver of a Dog,” Veterinary Pathology Online, Vol. 43, No. 6, 2006, pp. 1033-1036. doi:10.1354/vp.43-6-1033
[12] L. Monda and M. R. Wick, “S-100 Protein Immunostaining in the Differential Diagnosis of Chondroblastoma,” Human Pathology, Vol. 16, No. 3, 1985, pp. 287-292. doi:10.1016/S0046-8177(85)80016-2
[13] J. A. Regezi, R. J. Zaro, K. D. McClatchey, R. M. Courtney and J. D. Crissman, “Osteosarcomas and Chondrosarcomas of the Jaws: Immunohistochemical Correlations,” Oral Surgery, Oral Medicine, Oral Pathology, Vol. 64, No. 3, 1987, pp. 302-307. doi:10.1016/0030-4220(87)90009-0
[14] T. Charo, K. Matsumoto, M. Ishizawa, S. Morimoto, S. Hukuda and H. Okabe, “Periostal Osteosarcoma and Parosteal Chondrosarcoma Evaluated by Double Immunohistochemical Staining. Report of 2 cases,” Acta Orthopedica Scandinavica, Vol. 65, No. 3, 1994, pp. 355-358. doi:10.3109/17453679408995471
[15] M. P. Hoang, P. A. Suarez, L. R. Donner, J. Y. Ro, N. G. Ordnez, A. G. Ayala and B. Czemiak, “Mesenchymal Chondrosarcoma: A Small Cell Neoplasm with Polyphenotypic Differentation,” International Journal of Surgical Pathology, Vol. 8, No. 4, 2000, pp. 291-301. doi:10.1177/106689690000800408
[16] T. Kawano, J.-I. Hamada, M. Morioka, Y. Mihara, Y. Ishimaru, M. Kaku, Y. Ushio and J.-I. Kuratsu, “Skul Metastasis from Clear Cell Chondrosarcoma,” Neurologia Medico-Chirurgica (Tokyo), Vol. 45, 2005, pp. 367-370.
[17] J. P. Farese, J. Kirpensteijn, M. Kik, N. J. Bacon, S. S. Wattman, B. Seguin, M. Kent, J. Liptak, R. Straw, M. N. Chang, Y. Jiang and S. J. Withtow, “Biological Behavior and Clinical Outcome of 25 Dogs with Canine Appendicular Chondrosarcoma Treated by Amputation: A Veterinary Society of Surgical Oncology Retrospective Study,” Veterinary Surgery, Vol. 38, No. 8, 2009, pp. 914-919. doi:10.1111/j.1532-950X.2009.00606.x
[18] R. Casadei, M. Ricci, P. Ruggieri, R. Biagini, S. Benassi, P. Picci and M. Campanacci, “Chondrosarcoma of the Soft Tissues: Two Different Subgroups,” Journal of Bone and Joint Surgery, Vol. 73, 1991, pp. 162-168.

  
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