An implantable electrical stimulator for phrenic nerve stimulation

DOI: 10.4236/jbise.2012.53018   PDF   HTML     3,540 Downloads   6,167 Views   Citations

Abstract

Phrenic nerve stimulation is a technique whereby a nerve stimulator provides electrical stimulation of the phrenic nerve to cause diaphragmatic contraction in patients with respiratory failure due to cervical spinal cord injury. This paper presents an eigth-channel stimulator circuit with an output stage (electrode driving circuit) that doesn’t need off-chip blocking-capacitors and is used for phrenic nerve stimulation. This stimulator circuit utilizes only 1 output stage for 8 channels. The proposed current generator circuit in this stimulator reducing to a single step the translation of the digital input bits into the stimulus current, thus minimizing silicon area and power consumption. An 8 bit implementation is utilized for this current generator circuit. The average pulse width for this eight- channel stimulator with 1 mA current, 20 Hz frequency and 8 bits resolution, is 150 - 300 μs. The average power consumption for a single-channel stimulation is 38 mW from a 1.2 V power supply. This implantable stimulator system was simulated in HSPICE using 90 nm CMOS technology.

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Sardarzadeh, S. and Pooyan, M. (2012) An implantable electrical stimulator for phrenic nerve stimulation. Journal of Biomedical Science and Engineering, 5, 141-145. doi: 10.4236/jbise.2012.53018.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] DiMarco, A.F. (2009) Phrenic nerve stimulation in patients with spinal cord injury. Jornal of Respiratory Physiology & Neurobiology, 169, 200-209.
[2] Taira, T., Takeda, N., Itoh, K., Oikawa, A. and Hori, T. (2003) Phrenic nerve stimulation for diaphragm pacing with a spinal cord stimulator. Elsevier, 59, 128-132.
[3] Khong, P., Lazzaro, A. and Mobbs, R. (2010) Phrenic nerve stimulation: The Australian experience. Journal of Clinical Neuroscience, 17, 205-208. doi:10.1016/j.jocn.2009.06.012
[4] Liu, X., Demosthenous, A. and Donaldson, N. (2007) A fully integrated fail-safe stimulator output stage dedicated to FES stimulation. IEEE International Symposium on Circuits and Systems, New Orleans, 27-30 May 2007, 2076-2079. doi:10.1109/ISCAS.2007.378507
[5] Liu, X., Demosthenous, A. and Donaldson, N. (2008) An integrated implantable stimulator that is fail-safe without off-chip blocking-capacitors. IEEE Transactions on Biomedical Circuits and Systems, 2, 3.

  
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