Journal of Biomedical Science and Engineering

Volume 12, Issue 8 (August 2019)

ISSN Print: 1937-6871   ISSN Online: 1937-688X

Google-based Impact Factor: 0.66  Citations  h5-index & Ranking

Predictors for Predicting Temperature Optimum in Beta-Glucosidases

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DOI: 10.4236/jbise.2019.128033    494 Downloads   1,190 Views  Citations


This is the continuation of our studies on beta-glucosidase, which plays an important role in biological processes and recently strong interests focus on their potential role in biofeul production. In order to develop simple methods to predict the optimal working condition for beta-glucosidase, we used a 20-1 feedforward backpropagation neural network to screen possible predictors to predict the temperature optimum of beta-glucosidase from 25 amino-acid properties related to the primary structure of beta-glucosidases. The results show that the normalized polarizability index and amino-acid distribution probability can predict the temperature optimum of beta-glucosidase, which highlights a cost-effective way to predict various enzymatic parameters of beta-glucosidase.

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Yan, S. and Wu, G. (2019) Predictors for Predicting Temperature Optimum in Beta-Glucosidases. Journal of Biomedical Science and Engineering, 12, 414-426. doi: 10.4236/jbise.2019.128033.

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