Journal of Tuberculosis Research

Volume 7, Issue 2 (June 2019)

ISSN Print: 2329-843X   ISSN Online: 2329-8448

Google-based Impact Factor: 0.62  Citations  

Selection of Health Care Workers for Screening for Latent Tuberculosis Infection

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DOI: 10.4236/jtr.2019.72007    1,172 Downloads   2,272 Views  Citations


Introduction: The rate of latent tuberculosis infections (LTBIs) in health care workers (HCWs) is higher than that in non-HCWs. We studied to investigate the prevalence and risk factors of LTBIs and the acceptance rate for treatment of LTBI among HCWs in South Korea, a country with an intermediate tuberculosis (TB) burden. Methodology: LTBI screening was conducted for HCWs at a tertiary and a secondary hospital from April 2017 to August 2017. This was a retrospective study included all HCWs who underwent LTBI examination. HCWs were classified by the degree of risk into four groups, based on two factors: possibility of exposure to TB, and impact on patients at the time of TB onset in the HCWs. The interferon-gamma release assay was used for the diagnosis of LTBI. Results: A total of 1326 HCWs were included; they comprised 801 HCWs from a tertiary hospital and 525 from a secondary hospital. A total of 235 (17.7%) HCWs were diagnosed with LTBIs. According to risk classification, there was no significant difference (P = 0.24). In multivariate analysis, age was the only independent risk factor (P < 0.001). The acceptance rate for LTBI treatment was 60.43%, and there were no associated factors in multivariate analysis. Conclusions: HCWs did not show any significant difference in the rate of LTBI by the degree of risk, and age was the independent risk factor. LTBI screening should be conducted for all HCWs regardless of risk classification.

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J.Y., Park, J.Y., Kim, M.S., Kim, J.H. and Lee, J.-Y. (2019) Selection of Health Care Workers for Screening for Latent Tuberculosis Infection. Journal of Tuberculosis Research, 7, 65-76. doi: 10.4236/jtr.2019.72007.

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