Author(s)

Chenkai Zhu^1,2, Jinsong Liu³, Songling Huang³, Lizhe He^1,2, Xiaoye Cong^1,2, Chao Tan^1,2, Chris Rudd^1,2, Xiaoling Liu^1,2*

¹Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China.
²Ningbo Nottingham New Materials Institute, The University of Nottingham Ningbo China, Ningbo, China.
³Department of Technology, Sinoma Co., Ltd., Nanjing, China.

Currently, phosphate based glasses have been potential future biomaterial for medical application due to excellent cytocompatibility and fully bioresorbability. In this study, phosphate based glass system with composition of 48P₂O₅-12B₂O₃-(25-X)MgO-14CaO-1Na₂O-(X)Fe₂O₃ (X = 6, 8, 10) and

45P₂O₅-(Y)B₂O₃-(32-Y)MgO-14CaO-1Na₂O-8Fe₂O₃ (Y = 12, 15, 20), was prepared via a melting quenching process. The effect of replacing MgO with Fe₂O₃ and B₂O₃ on the structural, thermal, degradation properties of phosphate based glass was investigated. Fourier Transform Infrared (FTIR) spectroscopy and Raman spectroscopy analysis confirmed the polymerisation of phosphate based glass network with addition of Fe₂O₃, thus the processing window was observed to increase whilst the dissolution rate was reduced, attributed to the formation of Fe-O-P cross-link. As the effect on the glass structure stability was demonstrated by both B₂O₃ and MgO, the nonlinear variation of thermal stability and degradation behaviour was observed for glass system with substitution of MgO by B₂O₃. However, due to the lower dissolution rate of glass system when compared to the biocompatible phosphate based glass in preliminary study, the expected cytocompatibility could be confirmed in the downstream activities.

Phosphate Based Glass, Boron, Iron, Thermal Properties, Degradation Study

Zhu, C. , Liu, J. , Huang, S. , He, L. , Cong, X. , Tan, C. , Rudd, C. and Liu, X. (2017) The Effects of Fe₂O₃ and B₂O₃ on the Glass Structural, Thermal, in Vitro Degradation Properties of Phosphate Based Glasses. New Journal of Glass and Ceramics, 7, 100-115. doi: 10.4236/njgc.2017.74009.