Author(s)

Iliass Charif^1*, Najat Khalil¹, Abdelmalek Ousadden², El Bachir Benjelloun², Ouafae Slimani³, Fatima Zahra Fdili Alaoui³, Fatima Zahra Hijri⁴, Omar Mesbahi⁴, Adil Ibrahimi¹, Ihsane Mellouki¹

¹Hepatogastroenterology Service, Hassan II University Hospital. Faculty of Medicine and Pharmacy of Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
²Visceral Surgery Service, Hassan II University Hospital. Faculty of Medicine and Pharmacy of Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
³Gynecology Obstetrics Service, Hassan II University Hospital. Faculty of Medicine and Pharmacy of Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.
⁴Medical Oncology Service, Hassan II University Hospital. Faculty of Medicine and Pharmacy of Fez, Sidi Mohammed Ben Abdellah University, Fez, Morocco.

Background: Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the gastrointestinal tract. GIST are rare during pregnancy. We report here the case of a patient who was admitted in our university hospital for GIST discovered during the second trimester of pregnancy. She was 42 years old, in the fifth months of pregnancy. She was admitted for biliary colic pain with vomiting. On abdominal examination, we objectified a distended abdomen with uterine height of 18 cm and epigastric mass of 10 cm. Abdominal ultrasound and magnetic resonance imaging (MRI) showed a hepatic, tissue and cystic mass, developing at the expense of the left liver. Endoscopy objectified an aspect of extrinsic compression at the front of the stomach. A cesarean was scheduled at the 35^th month of pregnancy for fetal extraction and rescue. Exploration of the peritoneal cavity during surgery has objectified a hepatic highly vascularised mass reaching up to the umbilicus. This mass was unresectable. A postoperative CT scan revealed a large bilobed epigastric mass adhering to the stomach and the left liver. Histological and immunohistochemical study of hepatic process showed a gastrointestinal stromal tumor of high risk of malignancy. Conclusion: few cases have been reported in the literature on GIST during pregnancy showing the rarity of the condition that requires multidisciplinary care.

GIST, Pregnancy, Imatinib

Charif, I. , Khalil, N. , Ousadden, A. , Benjelloun, E. , Slimani, O. , Alaoui, F. , Hijri, F. , Mesbahi, O. , Ibrahimi, A. and Mellouki, I. (2014) Pregnancy with Gastric Stromal Tumor. Case Reports in Clinical Medicine, 3, 571-576. doi: 10.4236/crcm.2014.311124.