Modern Research in Inflammation

Volume 3, Issue 3 (August 2014)

ISSN Print: 2169-9682   ISSN Online: 2169-9690

Google-based Impact Factor: 0.25  Citations  

The Role of Gallium (Ga-67) Scintigraphy in the Diagnosis of Sarcoidosis

HTML  XML Download Download as PDF (Size: 1361KB)  PP. 99-107  
DOI: 10.4236/mri.2014.33012    6,593 Downloads   7,868 Views  Citations

ABSTRACT

Purpose: To identify and interrogate the role of Gallium-67 scintigraphy in the diagnosis of Sarcoidosis. Methods: A retrospective study of 75 patients with suspected Sarcoidosis in a large teaching hospital with a specialist Sarcoidosis Centre. Results: Ga-67 scintigraphy in patients considered on clinical grounds to have Sarcoidosis is a useful and sensitive test, and furthermore, by relaxing the interpretation of gallium scintigraphy sensitivity may be increased (from 20% to 80%) for a relatively small drop in specificity. Conclusions: The sensitivity of diagnostic power may be increased with a change in diagnostic criteria at the expense of only a small drop in specificity. In the context of Neurosarcoidosis, our results support the theory that Ga-67 scintigraphy has value in identifying potential, asymptomatic biopsy sites outside of the CNS that may not be identified by other forms of imaging.

Share and Cite:

Allard, A. , Buscombe, J. and Kidd, D. (2014) The Role of Gallium (Ga-67) Scintigraphy in the Diagnosis of Sarcoidosis. Modern Research in Inflammation, 3, 99-107. doi: 10.4236/mri.2014.33012.

Copyright © 2025 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.