Author(s)

Pierre Togo^1*, Hawa Konaré¹, Mariam Maïga², Karamoko Sacko¹, Djénéba Konaté¹, Abdoul Karim Doumbia¹, Adama Dembélé¹, Oumar Coulibaly¹, Aminata Sangaré¹, Mohamed Elmouloud Cissé¹, Fousseyni Traoré¹, Belco Maïga¹, Ibrahim Ahamadou¹, Aminata Doumbia¹, Lala N’Drany Sidibé¹, Amadou Touré¹, Yacouba Aba Coulibaly¹, Kalirou Traoré¹, Tati Simaga¹, Souleymane Sagara¹, Leyla Bagna Maïga¹, Bory Traoré¹, Abdoul Aziz Diakité¹, Fatoumata Dicko¹, Mariam Sylla¹, Sounkalo Dao³, Boubacar Togo¹

¹Paediatric Department, Gabriel Touré Teaching Hospital, Bamako, Mali.
²Pediatric Department, Distric VI Reference Health Center, Bamako, Mali.
³Infectious Diseases Department, Point G Teaching Hospital, Bamako, Mali.

Objectives: The main objective was to evaluate antibiotic prescribing in the Department of Pediatrics at Gabriel Touré teaching hospital. Methods: This was a prospective descriptive study conducted from September 1 to November 31, 2018, in the Department of Pediatrics at Gabriel Touré teaching hospital. All children aged 0 to 15 years hospitalized for any pathology during the study period and having received at least one antibiotic had been included. Results: We collected 445 children’s records out of 1032 admissions during the study period, representing a hospital frequency of 43.1%. The sex ratio was 1.3%. The 2 - 5 age group accounted for 48.1%. Fever was the reason for consultation in 45.6% of cases. Patients’ general condition was altered in 60% of cases. The fathers were blue-collar workers in 65.4% and the mothers housewives in 85%, and had no education in 42.9% and 64.5% respectively. Hepatomegaly was present in 18.2%, splenomegaly in 9.6% and peripheral adenopathy in 3.1%. The site of infection was pulmonary in 37.6% and ENT in 9.2%. Bacterial infection was assumed on admission in 54% of cases, and meningitis in 57.7%. The discharge diagnosis was malaria in 54.6%, severe acute malnutrition in 18.6% and meningitis in 6.7%. The death rate was 3.8%. Neutrophilic leukocytosis was present in 47.3% of patients. CRP was positive in 85% of patients. Blood cultures taken in 27.6% of patients were positive in 5. CSF analysis in 30% of patients showed elevated leukocytes in 6.5%. No cultures were positive. Antibiotic prescription was justified by infectious hypotheses in 43.1% of patients. β-lactam antibiotics were prescribed in 98.6%. Antibiotic therapy was not adapted to national/international recommendations in 68.3% of cases, and was not justified in 16.3% of cases on D5 of hospitalization. Conclusion: Antibiotic use was justified in more than half of patients, but remained inadequate in almost two-thirds of cases, in line with national and international recommendations.

Antibiotic Prescription, Hospitalization, Child

Togo, P. , Konaré, H. , Maïga, M. , Sacko, K. , Konaté, D. , Doumbia, A. , Dembélé, A. , Coulibaly, O. , Sangaré, A. , Cissé, M. , Traoré, F. , Maïga, B. , Ahamadou, I. , Doumbia, A. , Sidibé, L. , Touré, A. , Coulibaly, Y. , Traoré, K. , Simaga, T. , Sagara, S. , Maïga, L. , Traoré, B. , Diakité, A. , Dicko, F. , Sylla, M. , Dao, S. and Togo, B. (2024) Evaluation of Antibiotic Prescribing in the Pediatric Department of Gabriel Touré Teaching Hospital, Bamako, Mali. Open Journal of Pediatrics, 14, 645-656. doi: 10.4236/ojped.2024.143062.