Open Journal of Stomatology

Volume 12, Issue 11 (November 2022)

ISSN Print: 2160-8709   ISSN Online: 2160-8717

Google-based Impact Factor: 0.49  Citations  h5-index & Ranking

Pulp Revascularization: Future Therapy of Tooth with Open Apex

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DOI: 10.4236/ojst.2022.1211029    186 Downloads   1,224 Views  


Introduction: The endodontic management of necrotic permanent immature teeth is a challenge for the practitioner. These teeth are treated by apexification. However, because of the complications associated with this treatment, researchers have developed other therapies. Currently, a new technique called pulp revascularization has emerged. This technique allows the continuation of root completion thanks to a healthy tissue newly formed at the intra root canal level. Material and method: A literature search of articles dealing with pulp revascularization of immature permanent teeth was conducted using two types of search strategy, a literature search using keywords on databases and then a manual “bottom-up” search of references of previously identified articles. Results: 112 articles were identified based on inclusion and exclusion criteria. Discussion: This work showed that pulp revascularization is a new therapy that aims to restart root development on an immature permanent tooth. It is based on the principle of tissue engineering and uses the differentiation potential of stem cells. Conclusion: Currently, the literature values revascularization as it allows root development, sidewall thickening, apical closure and a decrease in periapical lesion and ensures a good sealing. Clinical and radiographic success rates appear to be encouraging, except that factors influencing treatment must be taken into consideration.

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Karami, M. , Skalli, R. , Jermouni, I. and Jabri, M. (2022) Pulp Revascularization: Future Therapy of Tooth with Open Apex. Open Journal of Stomatology, 12, 327-336. doi: 10.4236/ojst.2022.1211029.

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