Author(s)

Tomoro Morikawa¹, Yuki Tanabe¹, Tomoyuki Kido^1*, Ryo Ogawa¹, Masashi Nakamura¹, Sho Akasaka¹, Kouki Watanabe², Michaela Schmidt³, Osamu Yamaguchi⁴, Teruhito Kido¹

¹Department of Radiology, Ehime University Graduate School of Medicine, Ehime, Japan.
²Department of Cardiology, Saiseikai Matsuyama Hospital, Ehime, Japan.
³Siemens Healthcare GmbH, Allee am Roethelheimpark, Erlangen, Germany.
⁴Department of Cardiology, Pulmonology, Hypertension and Nephrology, Ehime University Graduate School of Medicine, Ehime, Japan.

Purpose: This study aimed to use gadolinium-enhanced cardiovascular magnetic resonance (LGE-CMR) scanning to examine the clinical feasibility of feature-tracking strain (FT-strain) analysis on compressed sensing (CS) cine cardiovascular magnetic resonance (CMR) imaging for detecting myocardial infarction (MI). Methods: We enrolled 37 patients who underwent conventional cine CMR, CS cine CMR, and LGE-CMR scanning to assess cardiovascular disease. FT-strain analysis was used to assess peak circumferential strain (p-CS) based on an 18-segment model in both cine CMR imaging modalities. Based on LGE-CMR imaging findings, myocardial segments were classified as remote, adjacent, subendocardial infarcted, and transmural infarcted. The diagnostic performance of p-CS for detecting MI was compared between CS cine CMR imaging and conventional cine CMR imaging using the receiver operating characteristic (ROC) curve analysis. Results: A total of 440 remote, 85 adjacent, 76 subendocardial infarcted, and 65 transmural infarcted segments were diagnosed on LGE-CMR imaging. There were significant between-group differences in p-CS on both conventional and CS cine CMR (p < 0.05 in each) imaging. The sensitivity and specificity of p-CS for identifying MI were 85% and 79% for conventional cine CMR imaging, and 82% and 77% for CS cine CMR imaging, respectively. There was no significant difference between conventional and CS cine CMR imaging in the area under the curve of p-CS (0.89 vs. 0.87, p = 0.15). Conclusion: FT-strain analysis of CS cine CMR imaging may help identify MI; it may be used alongside or instead of conventional CMR imaging.

Cardiovascular Magnetic Resonance, Cardiac Function, Compressed Sensing, Myocardial Infarction, Myocardial Strain

Morikawa, T. , Tanabe, Y. , Kido, T. , Ogawa, R. , Nakamura, M. , Akasaka, S. , Watanabe, K. , Schmidt, M. , Yamaguchi, O. and Kido, T. (2021) Feature-Tracking Strain Derived from Compressed Sensing Cine Cardiovascular Magnetic Resonance Imaging for Myocardial Infarct Detection: A Feasibility Study. Open Journal of Radiology, 11, 101-114. doi: 10.4236/ojrad.2021.113010.