Advances in Infectious Diseases

Volume 8, Issue 4 (December 2018)

ISSN Print: 2164-2648   ISSN Online: 2164-2656

Google-based Impact Factor: 0.64  Citations  h5-index & Ranking

Prognosis and Evolution of Lassa Virus Infected Persons during the 2017 Epidemic in Togo

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DOI: 10.4236/aid.2018.84022    500 Downloads   1,093 Views  


Introduction: Lassa viral hemorrhagic fever is common in West Africa. Almost 300,000 persons are affected each year with 5000 deaths. The mice of the genus mastomys is the wild tank. Objective: The aim of our study is to describe clinic, therapeutic and evolution of the affected patients during February-March 2017 epidemic that occurred in the north of Togo. Methodology: Our study is a record review study from patients’ record, who were hospitalized from February, 1st to March, 31st 2017 at Mango hospital. Lassa diagnosis was performed by PCR. They patients have received Ribavirin and blood transfusion when necessary. Results: We have reported 5 clinical observations of Lassa viral hemorrhagic fever. Patients came from Benin (03 cases), from Burkina-Faso (1 case), from Togo (1 case) and were 25, 34, 60, 52 years old and a premature baby of 13 days. External hemorrhage and abdominal pains were the main symptoms. Fever was observed for all the cases. Complications were marked by hemorrhages and shocks. Only 3 patients had benefitted of Antiviral therapy with Ribavirin. The other 2 patients did not benefit from the treatment because the diagnosis of Lassa fever was done the day they dead before the treatment started. Lethality was 80% (4 cases) with a highly secured burial. Effective management of contacts was done. Conclusion: Diagnostic and therapeutic delays of patients are responsible of the bad prognosis of the disease.

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Wateba, M. , Bawé, L. and Dossim, S. (2018) Prognosis and Evolution of Lassa Virus Infected Persons during the 2017 Epidemic in Togo. Advances in Infectious Diseases, 8, 262-267. doi: 10.4236/aid.2018.84022.

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