FSH/LH Ratio as a Predictor of the IVF Outcome in Young Women ()
Affiliation(s)
1Obstetrics and Gynaecology Department, Kasr Aini Hospital, Cairo University, Giza, Egypt.
2Centre of Fertility and Andrology Care (CFAC), Cairo, Egypt.
3Internal Medicine Department, Kasr Aini Hospital, Cairo University, Giza, Egypt.
4New Life Fertility Center, Mississauga, Canada.
ABSTRACT
In Vitro Fertilization (IVF) is the treatment for many causes of infertility.
Many studies were done to investigate different factors that can affect the
success rate. This study was conducted to evaluate if cycle day 3 (CD3) follicle-stimulating
hormone (FSH)/luteinizing hormone (LH) ratio
can be a predictor for the IVF outcome in young sub-fertile females ≤ 35 years
with normal baseline FSH. This is a retrospective case control study conducted at the Centre of
Fertility and Andrology Care (CFAC) in Egypt where 235 sub-fertile women
underwent IVF. Patients were grouped based on CD3 FSH/LH ratio. Group A consisted
of ≤35-year-old women with FSH/LH ratio < 2 and group B included ≤35-year-old
women with FSH/LH ratio ≥ 2. The primary outcomes include the fertilization
rate, implantation rate and the clinical pregnancy rate. The secondary outcomes
include duration and the total dose of gonadotrophin used. We found that, there
was no significant difference in the total dose of gonadotropin used during the
IVF cycle. Also, there was no significant difference in the number of retrieved and fertilized
oocytes and the number of good embryos. Clinical pregnancy rate was the same in
both groups. In conclusion, in patients younger
than 35 years, CD3 FSH/LH ratio is not a predictor for IVF outcome.
Share and Cite:
Shaeer, E. , Maged, A. , Shaheen, D. and Gomaa, H. (2018) FSH/LH Ratio as a Predictor of the IVF Outcome in Young Women.
Open Journal of Obstetrics and Gynecology,
8, 817-825. doi:
10.4236/ojog.2018.810085.