Author(s)

Momen S. A. Abdelaty^1*, Dirk Kuckling²

¹Polymer Lap, Chemistry Department, Faculty of Science (Assiut), Al-Azhar University, Assiut, Egypt.
²Chemistry Department, University of Paderborn, Paderborn, Germany.

This article reports on the synthesis of acrylate monomer from renewable material. Vanillin was selected to be the start material to produce new monomer called vanillin acrylate and abbreviated by (VA). It has been successfully investigated by ¹H, ¹³C NMR, IR and UV and all results were in logic state. The next step was to synthetize three different thermo-responsive functional copolymers by incorporation of three different molar ratios of vanillin acrylate (10, 20, 30 mol%) with N-Isopropylacrylamide via free radical polymerization by AIBN as initiator in solution. All copolymers were deduced by ¹NMR and IR and all showed the presence of aldehyde group. The copolymer was used for grafting of tryptophan and β-alanine through the chemical link between amino group and the active aldehyde group by click reactions to form Schiff’s base imine compounds. Moreover, polymers were also elucidated by ¹HNMR, IR and UV, Size Exclusion Chromatography (SEC) was used for the molecular weight determination, differential scanning calorimeter (DSC) for glass temperature of solid polymers, XRD for crystallinity. UV-vis Spectroscopy was used for the determination of phase separation or the lower critical solution temperature (T_c) of polymers solution not only in deionized water but in pH5 and pH11. The mount of conversation and linked amino acid was determined by UV-vis Spectroscopy.

Dual Responsive Polymers, Functional Polymers, Grafting, Amino Acids, Schiff’s Base, Click Reactions

Abdelaty, M. and Kuckling, D. (2018) Poly (N-Isopropyl Acrylamide-Co-Vanillin Acrylate) Dual Responsive Functional Copolymers for Grafting Biomolecules by Schiff’s Base Click Reaction. Open Journal of Organic Polymer Materials, 8, 15-32. doi: 10.4236/ojopm.2018.82002.