Journal of Cancer Therapy

Volume 9, Issue 3 (March 2018)

ISSN Print: 2151-1934   ISSN Online: 2151-1942

Google-based Impact Factor: 0.52  Citations  h5-index & Ranking

Comparing Nasal Cavity Radiotherapy Using Electron, Photon, Proton and Photon-Electron Beams

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DOI: 10.4236/jct.2018.93022    525 Downloads   1,006 Views  

ABSTRACT

Aim: Electron, photon or proton beams are used in radiotherapy for cancer treatment while each one may be used depending on depth and the location of tumor and normal tissues around the treatment target as well as economic issues. Materials and Methods: In this research, dose distribution by proton was measured by film dosimetry in nasal cavity Plexiglas phantom and Monte Carlo simulation. Then the DVH of treatment target and the posterior of treatment target of different beams were compared. The energies of electron, photon and proton were 9 MeV, 6 MV, and maximum 65 MeV, respectively. Due to a depth of 3.5 cm of CTV (Clinical Target Volume), Modulation Range was between 0 - 3.5 cm and SOBP (Spread-out Bragg Peak) was between 0 - 65 MeV. Results: Comparing the obtained DVH values, 95% dose coverage of target volume for electron, photon, proton and Photon-Electron beams were 88%, 98%, 98%, and 95%, respectively. However, doses above 40% that reached outside the target were 50%, 82%, 5%, and 44%, respectively. Conclusions: The results demonstrate the superiority of proton therapy in nasal cancer due to its better target volume coverage and the less amount of the dose reaching outside the target that is because of dose discharge in a small area and significant dose fall-off after Bragg peak.

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Khaledi, N. , Ahmadabad, F. , Ebam, S. and Hosseinabadi, R. (2018) Comparing Nasal Cavity Radiotherapy Using Electron, Photon, Proton and Photon-Electron Beams. Journal of Cancer Therapy, 9, 255-261. doi: 10.4236/jct.2018.93022.

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