Prevalence and Risk Factors of Peripheral Artery Disease in a Group of Apparently Healthy Young Cameroonians: A Cross-Sectional Study - World Journal of Cardiovascular Diseases

WJCD > Vol.8 No.2, February 2018

World Journal of Cardiovascular Diseases

Volume 8, Issue 2 (February 2018)

ISSN Print: 2164-5329 ISSN Online: 2164-5337

Google-based Impact Factor: 0.38 Citations

Prevalence and Risk Factors of Peripheral Artery Disease in a Group of Apparently Healthy Young Cameroonians: A Cross-Sectional Study ()

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DOI: 10.4236/wjcd.2018.82011 1,137 Downloads 2,557 Views Citations

Author(s)

Félicité Kamdem^1,2, Yacouba Njankouo Mapoure^1,2, Ba Hamadou³, Fanny Souksouna², Ahmadou Musa Jingi³, Caroline Kenmegne¹, Fernando Kemta Lekpa¹, Jaff Fenkeu Kweban¹, Gisèlei Mandy⁴, Jean Pierre Nda Mefo’o^2,4, Henry Luma^1,3, Marie Solange Doualla^1,3

Affiliation(s)

¹Internal Medicine Service, Douala General Hospital, Douala, Cameroon.
²Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
³Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.
⁴Chemical Pathology Laboratory, Douala General Hospital, Douala, Cameroon.

ABSTRACT

Background: The burden of peripheral artery disease (PAD) is not well known among apparently healthy people in Africa. Aim: To determine the prevalence and associated risk factors of PAD in a group of blood donors seen at the Douala General Hospital—Cameroon. Methods: Between 1^st November 2015 and 30^th April 2016, we carried out a cross-sectional study. Participants were consenting adults of both sexes, aged ≥ 21 years who presented for blood donation, and were tested HIV negative. We collected socio-demographic data and their past history. We carried out a physical examination and measured their Ankle-Brachial Index (ABI). We defined PAD as an ABI < 0.9. We also measured their fasting blood glucose and lipid profile. Results: We recruited 103 participants, 55.4% males. The mean age was 33 ± 10 years. The mean ABI on left and right leg was 1.04 ± 0.1 and 1.02 ± 0.1respectively. ABI was higher in males than females both legs (p < 0.05). PAD was seen in 11 (10.7%) participants. This was higher in females than males (3.6% versus 19.2%, p = 0.026). Among those with PAD, 8 (72.7%) were asymptomatic (Males: 100% versus Females: 66%, p = 0.9). After adjusting for age and gender, sedentary lifestyle (aOR: 7.14, [95% CI: 1.38 - 33.3], p = 0.019), and female gender (aOR: 6.2, [95% CI: 1.26 - 30.5], p = 0.025) were significantly associated with PAD. Conclusion: The prevalence of PAD was high in this group of HIV negative blood donors, most of whom were asymptomatic. This was associated with females, and a sedentary lifestyle.

KEYWORDS

Peripheral Artery Disease, ABI, Prevalence, Risk Factors, Douala

Share and Cite:

Kamdem, F. , Mapoure, Y. , Hamadou, B. , Souksouna, F. , Jingi, A. , Kenmegne, C. , Lekpa, F. , Kweban, J. , Mandy, G. , Mefo’o, J. , Luma, H. and Doualla, M. (2018) Prevalence and Risk Factors of Peripheral Artery Disease in a Group of Apparently Healthy Young Cameroonians: A Cross-Sectional Study. World Journal of Cardiovascular Diseases, 8, 111-122. doi: 10.4236/wjcd.2018.82011.

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