Author(s)

Mussa H. Almalki^*, Badurudeen Mahmood Buhary, Imad Brema, Abdulrahman Almaghamsi, Saad Al Zahrani

Obesity, Endocrine and Metabolism Centre, King Fahad Medical City (KFMC), Riyadh, Saudi Arabia.

Ectopic posterior pituitary is a disruption in the normal embryogenesis and is one of the rare but common causes of pituitary dwarfism. We report the MRI and clinical findings of a 13.5-year-old Saudi boy who was referred to the endocrine outpatient clinic with no significant complaints except for fatigue, exercise intolerance and short stature. Physical examination revealed short stature (below 2^nd centile) with normal body proportion without any dysmorphic features and prepubertal secondary sexual characteristics and genitalia. Hormonal profile revealed: low thyroxine level, low gonadotrophins, low testosterone, low cortisol and blunted growth hormone (GH) response to insulin induced hypoglycaemia. Bone age was of 5 years old. The MRI result concluded with a diagnosis of ectopic posterior pituitary. A diagnosis of posterior pituitary ectopia (PPE) with panhypopituitarism was made.

Panhypopituitarism, Posterior Pituitary Ectopia, Growth Hormone Deficiency, Short Stature

Almalki, M. , Buhary, B. , Brema, I. , Almaghamsi, A. and Zahrani, S. (2017) Short Stature due to Ectopic Neurohypophysis: Case Report. Open Journal of Endocrine and Metabolic Diseases, 7, 89-95. doi: 10.4236/ojemd.2017.72009.