Esophageal Cancer in Sudan: Demographic and Histopathlogical Variations - Open Journal of Gastroenterology

OJGas > Vol.7 No.3, March 2017

Open Journal of Gastroenterology

Volume 7, Issue 3 (March 2017)

ISSN Print: 2163-9450 ISSN Online: 2163-9469

Google-based Impact Factor: 0.23 Citations

Esophageal Cancer in Sudan: Demographic and Histopathlogical Variations ()

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DOI: 10.4236/ojgas.2017.73014 1,755 Downloads 3,651 Views Citations

Author(s)

Asma Mahir Hamad¹, Mohamed Elbagir K. Ahmed^2*, Abdulfattah Abdelgadir³, Ikhlas B. Suliman⁴

Affiliation(s)

¹Sunderland Royal Hospital, Sunderland, UK.
²College of Medicine, King Khalid University, Abha, KSA.
³University of Medical Sciences & Technology, Khartoum, Sudan.
⁴Ministry of Health, Khartoum, Sudan.

ABSTRACT

Background: Sudan is experiencing a growing cancer problem. Esophageal cancer (EC) is a devastating disease with high mortality. Our objective was to study the demographic factors and histopathological pattern of EC cancer in Khartoum, Sudan. Methods: In a retrospective cross-sectional study, the records and histopathology reports of all patients diagnosed endoscopically as EC and who were referred to Zain center, a reference histopathology center in Khartoum Sudan, were studied over a 6-month period. Descriptive and simple statistics were used for analysis. Results: Out of 74 histopathologically studied patients, 66 (89.2%) had squamous cell (SCC) cancer (average age 59 y, mainly females) and 8 (10.8%) had adenocarcinoma (AC-average age 69 y). The female to male ratio is 1.5:1. In females with SCC, the tumors mainly located in the upper and middle thirds of the oesophagus. On the other hand, 6 out of the 8 patients with AC were men, with the tumors located mainly in the lower third. Conclusions: In Khartoum, Sudan, esophageal cancer affects females (predominantlySCC) more than males (predominantly AC). It occurs at a relatively young age, and is predominantly squamous cell in type. No specific risk factors were identified and this needs further studies.

KEYWORDS

Esophagus, Cancer, Histopathology, Sudan

Share and Cite:

Hamad, A. , Ahmed, M. , Abdelgadir, A. and Suliman, I. (2017) Esophageal Cancer in Sudan: Demographic and Histopathlogical Variations. Open Journal of Gastroenterology, 7, 124-129. doi: 10.4236/ojgas.2017.73014.

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[2]	Epidemiology, Risk Factors and Management of Esophageal Cancer in East of Sudan (Single center experience from 2016-2018)
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[3]	Genetic analysis of TP53 gene mutations in exon 4 and exon 8 among esophageal cancer patients in Sudan
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[4]	Histopathology, Immunohistochemistry and Molecular Study of Tumor Protein 53 Gene Mutations in Esophageal Cancer among Sudanese Patients
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[5]	Identification of HER 2-neu in Esophageal Carcinoma by Immunohistochemical technique among Sudanese Patients
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